Biomolecules & Therapeutics
- Volume 9 Issue 3
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- Pages.188-193
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- 2001
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- 1976-9148(pISSN)
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- 2005-4483(eISSN)
Effects of the Grapevine Shoot Extract on Free Radical Scavenging Activity and Inhibition of Pro-inflammatory mediator Production in RAW264.7 Macrophages
포도나무가지 추출물의 프리라디칼 소거 작용 및 염증 발현 매개인자 생성 억제 효과
Abstract
Free radical scavengers or quenching agents for reactive oxygen species (ROS) present in consumable fruits, vegetables, and beverages have received considerable attention as potential antioxidants, and thus uses for treatment of several human diseases. In this study, grapevine shoot extract (GSE) containing high concentration of resveratrol and viniferine was evaluated for antioxidant potential and inhibition of pro-inflam-matory mediator production. Utilizing 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenging activity and xanthine oxidase (XOD) inhibition assay the GSE showed inhibitory effects of DPPH radical scavenging and XOD activity with the
Keywords
- Grapevine shoot extract (GSE);
- Antioxidant activity;
- Prostaglandin E$_2$;
- Nitric oxide;
- Antiin-flammatory agent