Some Pharmacological Activities of Acanthoic Acid Isolated from Acanthopanax koreanum Root Bark

섬모갈피나무의 근피성분, Acanthoic acid의 약리작용

Some pharmacological activities of acanthoic acid, isolated from Acanthopanax koreanum root was investigated in animals. It is revealed that the compound had analgesic and anti-inflammatory activities without actions on central nervous system and showed inhibition of lipid peroxidation. The anti-inflammatory activity might be related to inhibition of prostaglandin E$_2$ synthesis in exudates of inflammation.