The Investigation of Synovial Fluid and Serum for Biochemical Markers of Joint Diseases in the Horse

말의 활액 및 혈청 분석을 통한 관절질환의 생화학적 예측 인자

  • Published : 2001.09.01

Abstract

The joint disease including osteoarthris (OA) and rheumatoid arthritis (RA) are common in the horse. Many studies have been performed to develop biochemical markers reflecting the abnormalities of cartilage and synovial membrane. However, no specific, sensitive and clinically well established assay systems have been yet available to characterize the severity of joint diseases. Indeed, radiography is still doctor's best choice of assessing joint damage in OA/RA. This review focuses on biochemical molecules such as proteoglycan, collagen, matrix metalloproteinases (MMPs), lectin and cytokine to assess their potential value for not only predicting stage of joint disease but also monitoring treatment efficacy.

Keywords

References

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