식도-위 절제술 후 횡격막 crura의 역할

Role of Crural Diaphragm after Esophagogastrectomy

  • 조성래 (고신대학교 의학부 흉부외과학교실) ;
  • 하현철 (고신대학교 의학부 흉부외과학교실) ;
  • 이봉근 (고신대학교 의학부 흉부외과학교실) ;
  • 조봉균 (고신대학교 의학부 흉부외과학교실)
  • 발행 : 2001.10.01

초록

배경: 식도-위 접합부에 존재하는 고압력대는 위-식도 역류를 예방하는 중요한 역할을 하는데 주로 하부 식도 괄약근이 관여한다. 그러나 하부 식도괄약근이 제거된 환자에서 횡격막 crura가 고압력대로 나타나 괄약양의 역할을 하는 지를 알아보기 위하여 식도 내압을 측정하였다. 대상 및 방법: 식도-위 절제술을 시행받은 환자 22명과 대조군으로 정상 성인 3명을 대상으로 식도 내압을 측정하였다 결과: 대조군은 3명 전원에서, 환자는 22명중 12명에서 고압력대가 나타났는데 Ivor-Lewis법 수술을 시행받은 환자보다는 좌측 개흉을 시행받은 환자에서 많이 나타났다. 고압력대의 위치는 환자군에서 비강으로부터 42.5$\pm$0.9cm로 대조군과 비슷한 위치에서 나타났으나, 길이는 2.13$\pm$0.6cm로 대조군 보다 짧았다. 고압력대의 압력은 station pull-through technique(SPT), rapid pull-through technique(RH)에 의해 측정한 결과 각각 13.78$\pm$1.63mmHg, 28.58$\pm$6.06 mmHg로 대조군 보다낮았으며, 부분적으로 연하에 의해 이완되고(84.4%), 복압증가에 의해 수축하는 양상을 보였다. 결론: 하부 식도 괄약근이 제거된 경우에도 횡격막 crura에 의해 흉복부 접합부에 고압력대가 나타나며, 이 횡격막 crura가 괄약양 역할을 하기 때문에 식도-위 절제술후 손상된 횡격막 crura의 복구를 시행함으로써 위-식도 역류를 감소시킬 수 있을 것으로 사료된다.

Background: The high pressure zone(HPZ) at the gastroesophageal junction is an important barrier for prevention of gastroesophageal reflux. Smooth muscle layers in the lower esophageal sphincter mainly contributes to HPZ at the throacoabdominal junction. The purpose of this study was to investigate the manometric characteristics of the thora-coabdominal junction in patients after surgical removal of the lower esophageal sphincter. Material and Method: Twenty two patients with prior esophagogastrectomy(10 Ivor-Lewis method and 12 left thoracotomy) and 30 normal adults(control group) were studied manometrically. Result: Esophageal manometry showed a HPZ and pressure inversion points distal to the anastomosis in 12 of 22 patients(2 of 10 patients with Ivor-Lewis method and 10 of 12 patients with left thoracotomy) and a HPZ in 30 of 30 normal adults. The location of HPZ front nostril was not significant different between the two groups(42.5$\pm$0.9cm in patients and 43.9$\pm$2.1cm in the control), while the length of HPZ was shorter in patients than in the control(2.13$\pm$0.6cm vs 2.83$\pm$0.59cm). By SPT and RPT, pressures of HPZ at rest were lower in patients(13.78$\pm$1.63mmHg, 28.58$\pm$6.06mmHg) than in control(20.3$\pm$4.95mmHg, 42.80$\pm$15.91mmHg). The HPZ relaxed partially in response to deglutition(84.4% in patient, 90.5% in control group) and contracted in response to increased intra- abdominal pressure induced by leg lifts(HPZ/ Intra-abdominal pressure= 1.81$\pm$0.23 in patient, 2.13$\pm$ 0.58 in control group).

키워드

참고문헌

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