생후 6개월 이하 환아에서 대동맥 축착증과 심실중격결손의 일차 완전교정

Single-Stage Repair of Coarctation of the Aorta and Ventricular Septal Defect in Infants Younger than 6 Months

  • 백만종 (부천세종병원 흉부외과, 세종심장연구소) ;
  • 김웅한 (부천세종병원 흉부외과, 세종심장연구소) ;
  • 이영탁 (성균관대학교 의과대학 삼성서울병원 흉부외과) ;
  • 한재진 (이화여자대학교 의과대학 흉부외과) ;
  • 이창하 (부천세종병원 흉부외과, 세종심장연구소)
  • 발행 : 2001.10.01

초록

배경: 대동맥 축착증과 심실중격결손이 동반된 환아의 적절한 치료 방침에 대해서는 이견이 많다. 본 연구는 생후 6개월 이하의 환아에서 대동맥 축착증과 심실중격결손의 일타 완전교정 결과 및 수술방법에 따른 대동맥 축착증의 재발에 대해 알아보고자 하였다. 대상 및 방법: 1995년 1월부터 2000년 12월가지 본원에서 대동맥 축착증과 심실중격결손으로 일차 완전교정을 시행받은 생후 6개월 이하의 환아 33명을 대상으로 후향적으로 조사하였다. 환아의 평균 연령과 체중은 각각 54$\pm$37일(12일~171일)과 3.9$\pm$1.1kg(1.5~6kg)이었다. 대동맥 축착 고정은 연구 초기에는 저체온하 완전순환정지하에서 시행하였으며 최근에는 순환정지없이 무명동맥을 통한 국소 뇌관류 상태에서 시행하였다. 축착증 교정 방법은 초기에는 Extended cad-to-end anastomosis(EEEA;n=16)와 Extended side-to-side anastomosis(ESSA;n=2)를, 최근에는 Extended end-to-sidc anasto mosis(EESA;n=15)를 이용하였다 심실중격결손은 초기 16명에서는 Dacron을, 최근 17명에서는 자가 심낭편을 이용하여 폐쇄하였다. 대동맥궁 발육부전은 29명(88%)에서 있었으며 원위부 발육부전 18명, 완전형 5명, 그리고 복잡형은 6명이었다.

Background: The optimal therapeutic strategies for patients with coarctation of the aorta(CoA) and ventricular septal defect(VSD) remain controversial. This study was undertaken to determine the outcome and the need for reintervention following single-stage repair of coarctation with VSD in infants younger than 6 months. Material and Method: Thirty three consecutive patients who underwent single-stage repair of CoA with VSD, from January 1995 to December 2000, at Sejong General Hospital were reviewed retrospectively. Mean age and body weight at repair were 54$\pm$37 days(12 days-171 days) and 3.9$\pm$1.1 kg(1.5~6 kg), respectively. The surgical repair of CoA was performed under deep hypothermic circulatory arrest(CA) in the early period of the study and under regional cerebral perfusion through a direct innominate arterial cannulation without CA in the later period. The technique used in the repair of the CoA was resection and extended end-to-end anastomosis(EEEA; n=16) and extended side-to-side anastomosis(ESSA; n=2) in the early period, and resection and extended end-to-side anastomosis(EESA; n= 15) in the later period. The simultaneous closure of VSD was done with a Dacron patch(n= 16) and autologous pericardium(n=17). Aortic arch hypoplasia was present in 29 patients(88%) and its types were distal(n=18), complete(n=5), and complex(n=6)

키워드

참고문헌

  1. J Thorac Cardiovase Surg no.108 Outcomes in seriously ill neonates with coarctation of the aorta Quaegebeur JM;Jonas RA;Weinberg AD;Blackstone EH;Kirklin JW.
  2. Ann Thorac Surg no.58 Transternal repair of coarctation and associated cardiac defects Deleon SY;Downey FX;Baumgartner NE;Ow EP;Quinones JA;Torres L;Ilbawi MN;Pifarre R.
  3. J Thorac Cardiovasc Surg no.109 Surgical management of neonatal coarctation Conte S;Lacour-Gayet F;Serraf A;Sousa-Uva M;Bruniaux J;Touchot A;Planche C.
  4. J Thorac Cardiovasc Surg no.111 Decision making for the surgical management of aortic coarctation associated with ventricular septal defect Brouwer RMHJ;Cromme-Dijkhuis AH;Erasmus ME;Contant C.
  5. Eur J Cardiothorac Surg no.17 Single-stage repair of aortic coarctation with ventricular septal defect using isolated cerebral and myocardial perfusion Ishino K;Kawada M;Irie H;Kino K;Sano S.
  6. Eur J Cardiothorac Surg no.17 Primary repair of aortic arch ovstruction with ventricular septal defect in preterm and low birth weight infants Haas F;Goldberg CS;Ohye RG;Mosca RS;Bove EL.
  7. Eur J Cardiothorac Surg no.18 Outcome following single-stage repair of coarctation with ventricular septal defect William Gaynor J;Wernovsky G;Rychik J;Rome JJ;Decampli WM;Spray TL.
  8. J Thorac Cardiovasc Surg no.96 Aortic coarctation with hypoplastic aortic arch: results of extended end-to-end aortic arch anastomosis Vouhe PR;Trinquet F;Lecompte Y;et al.
  9. J Thorac Cardiovasc Surg no.107 Surgical treatment of aortic coarctation in infants younger than three months: 1985 to 1990 Van Heurn LWE;Wong CM;Spiegelhalter DJ;et al.
  10. Ann Thorac Surg no.61 Coarctation repair using end-to-side anastomosis of descending aorta to proximal aortic arch Rajasinghe HA;Reddy VM;van Son JA;et al.
  11. Ann Thorac Surg no.66 Repair of coarctation with resection and extended end-to-end anastomosis Backer CL;Mavroudis C;Zias EA;Amin Z;Weigel TJ.
  12. Circulation no.53 Anomalies of the aortic arch and ventricular septal defects Moulaert AJ;Bruins CC;Oppenheimer-Dekker A.
  13. 대한흉부외과학회지(인쇄중) 관전순환정지와 심근허혈 없이 시행한 변형 Norwood 술식 -2 례 보고- 백만종;김웅한;전양빈 등
  14. Circulation no.74 Extended aortic arch anastomosis for repair of coarctation in infancy Lansman S;Shapiro JA;Schiller MS;et al.
  15. Ann Thorac Surg no.52 Coarctation: do we need to resect ductal tissue? Jonas RA.
  16. J Thorac Cardiovasc Surg no.102 Patterns of ductal tissue in coarctation of the aorta in the first three months of life Russell GA;Berry PJ;Watterson K;Dhasmana JP;Wisheart JD.
  17. Ann Thorac Surg no.56 Aortic coarctation with hypoplastic arch in neonates: a spectrum of anatomic lesions requiring different surgical options Zannini L;Gargiulo G;Albanese SB;et al.
  18. J Am Coll Cardiol no.8 Quantitative morphology of the aortic arch in neonatal coarctation Morrow WR;Huhta JC;Murphy DJ;McNamara DG.
  19. Ann Thorac Surg no.52 Coarctation and hypoplasia of the aortic arch: will the arch grow? Siewers RD;Ettedgui J;Pahl E;Tallman T;del Nido PJ.
  20. J Card Surg no.12 Repair of coarctation of the aorta in neonates and young infants Van Son JAM;Falk V;Schneider P;Smedts F;Mohr FW.