인공판막 심내막염에서 판막간 섬유체 재건을 이용한 대동맥판 및 승모판 치환술

Aortic and Mitral Valve Replacement with Reconstruction of the Intervalvular Fibrous Skeleton in Prosthetic Valve Endocarditis

  • 백만종 (부천세종병원 흉부외과, 세종심장연구소) ;
  • 김욱성 (인제대학교 의과대학 일산 백병원 흉부외과) ;
  • 오삼세 (부천세종병원 흉부외과, 세종심장연구소) ;
  • 전양빈 (가천의과대학부속 길병원, 흉부외과) ;
  • 류재욱 (부천세종병원 흉부외과, 세종심장연구소) ;
  • 공준혁 (부천세종병원 흉부외과, 세종심장연구소) ;
  • 임청 (부천세종병원 흉부외과, 세종심장연구소) ;
  • 김수철 (부천세종병원 흉부외과, 세종심장연구소) ;
  • 김웅한 (부천세종병원 흉부외과, 세종심장연구소) ;
  • 나찬영 (부천세종병원 흉부외과, 세종심장연구소) ;
  • 이석기 (부천세종병원 흉부외과, 세종심장연구소) ;
  • 이창하 (가천의과대학부속 길병원, 흉부외과) ;
  • 이영탁 (성균관대학교 의과대학 삼성서울병원 흉부외과) ;
  • 윤용웅 (경희의료원 흉부외과학교실) ;
  • 박영관 (부천세종병원 흉부외과, 세종심장연구소) ;
  • 김종환 (부천세종병원 흉부외과, 세종심장연구소)
  • Baek, Man-Jong (Department of Thoracic and Cardiovascular Surgery, Sejong General Hospital, Sejong Heart Institute) ;
  • Kim, Wook-Sung (Department of Thoracic and Cardiovascular Surgery, Ilsan Paik Hospital, Inje University, College of Medicine) ;
  • Oh, Sam-Se (Department of Thoracic and Cardiovascular Surgery, Sejong General Hospital, Sejong Heart Institute) ;
  • Jeon, Yang-Bin (Department of Thoracic and Cardiovascular Surgery, Gachon Medical College, Gil Heart Center) ;
  • Ryu, Jae-Wook (Department of Thoracic and Cardiovascular Surgery, Sejong General Hospital, Sejong Heart Institute) ;
  • Kong, Joon-Hyuk (Department of Thoracic and Cardiovascular Surgery, Sejong General Hospital, Sejong Heart Institute) ;
  • Lim, Cheong (Department of Thoracic and Cardiovascular Surgery, Sejong General Hospital, Sejong Heart Institute) ;
  • Kim, Soo-Cheol (Department of Thoracic and Cardiovascular Surgery, Sejong General Hospital, Sejong Heart Institute) ;
  • Kim, Woong-Han (Department of Thoracic and Cardiovascular Surgery, Sejong General Hospital, Sejong Heart Institute) ;
  • Na, Chan-Young (Department of Thoracic and Cardiovascular Surgery, Sejong General Hospital, Sejong Heart Institute) ;
  • Lee, Seong-Ki (Department of Thoracic and Cardiovascular Surgery, Sejong General Hospital, Sejong Heart Institute) ;
  • Lee, Chang-Ha (Department of Thoracic and Cardiovascular Surgery, Gachon Medical College, Gil Heart Center) ;
  • Lee, Young-Tak (Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, School of Medicine, SungKyunkwan University) ;
  • Yoon, Youg-Woong (Department of Thoracic and Cardiovascular Surgery, KyungHee University Medical Center) ;
  • Park, Young-Kwang (Department of Thoracic and Cardiovascular Surgery, Sejong General Hospital, Sejong Heart Institute) ;
  • Kim, Chong-Whan (Department of Thoracic and Cardiovascular Surgery, Sejong General Hospital, Sejong Heart Institute)
  • Published : 2001.07.01

Abstract

대동맥판과 승모판 및 두 판막간 섬유체(fibrous skeleton)를 침범한 복잡 심내막염은 치료가 매우 어려운 질환의 하나로 여전히 술후 사망률과 이환율이 높다. 저자들은 좌측 대동맥판륜 농양 및 섬유체를 파괴한 인공 대동맥판 및 승모판막 심내막염이 동반된 55세 여자 환자에서 섬유체의 재건과 함께 대동맥판 및 승모판 치환을 하였던 예를 보고한다. 환자는 과거에 대동맥판과 승모판을 기계판막으로 두 번 치환술을 받았었다. 심장초음파 검사에서 비관상동의 판막 주위 결손 및 섬유체를 따라 비정상적인 누출 경로가 관탈되었다. 지속적으로 항생제를 투여하여도 혈액에서 staphylococcus epidermidis가 배양되고 지속되는 패혈증 증세를 보여 응급수술을 시행하였다. 대동맥 절개를 좌심방 지붕가지 확장한 다음 두 판막 및 판막간 섬유체를 완전히 절제한 다음 발견된 대동맥판륜 농양은 절제 후 소 심낭 패취를 이용하여 폐쇄하였다. 두 개의 삼각형 모양의 소 심낭 패취를 이용하여 절제된 대동맥 판과 승모판의 각각의 판륜 및 섬유체를 재건한 다음 기계판막을 대치하였다. 술후 지속적인 항생제 투여 후 심내막염 재발 소견이 없어 72일째 퇴원하였다. 술후 8개월에 시행한 심장초음파 검사에서 판막주위 누출이나 심내막염 재발 소견이 없었고 특별한 증세없이 통원치료중이다.

Patients who have complex endocarditis with involvement of both the aortic and mitral valves and intervalvular fibrous skeleton are among the most difficult to treat and still have the highest surgical mortality and morbidity rates. We report one case of aortic and mitral valve replacement with reconstruction of the fibrous skeleton performed in a 55-year-old female patient who had an aortic annular abscess and both the aortic and mitral prosthetic valve endocarditis with destruction of the fibrous skeleton. Previously, she had undergone redo double valve replacement\`, Transesophageal echocardiogram showed the paravalvular defect at the noncoronary aortic sinus and abnormal sinus tract along the fibrous skeleton. Emergent operation was performed due to positive blood cultures of staphylococcus epidermidis and persistent sepsis despite appropriate antibiotic therapy. After aortotomy extended to the roof of left atrium, both prosthetic valves and destroyed fibrous skeleton were completely resected and the aortic annular abscess was debrided and closed with a bovine pericardial patch. Reconstructions of both aortic and mitral annuli and the fibrous skeleton were done by using two separate bovine pericardial patches in triangular shape and mechanical valves were implanted. Postoperatively, adequate antibiotic therapies were continued and the patient was discharged at the postoperative 72 days without evidence of recurrence of endocarditis. Transthoracic echocardiogram of the postoperative 8 months shows no paravalvular leakage or recurrence of endocarditis and the patient has been followed up with no symptom.

Keywords

References

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