Journal of Chest Surgery

The Korean Society for Thoracic and Cardiovascular Surgery (대한심장혈관흉부외과학회)
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Langerhans' Cell Histiocytosis in Chest Wall

소아의 흉벽에 발생한 Langerhans 세포 조직구증의 치료 - 1례 보고 -

  • Song, Dong-Seop (Department of thoracic and cardiovascular surgery, College of medicine, Hanyang University) ;
  • Lee, Heng-Ok (Department of thoracic and cardiovascular surgery, College of medicine, Hanyang University) ;
  • Chung, Won-Sang (Department of thoracic and cardiovascular surgery, College of medicine, Hanyang University) ;
  • Kang, Jung-Ho (Department of thoracic and cardiovascular surgery, College of medicine, Hanyang University) ;
  • Kim, Young-Hak (Department of thoracic and cardiovascular surgery, College of medicine, Hanyang University) ;
  • Kim, Hyuck (Department of thoracic and cardiovascular surgery, College of medicine, Hanyang University) ;
  • Lee, Chul-Bum (Department of thoracic and cardiovascular surgery, Kuri Hospital, College of medicine, Hanyang University) ;
  • Ham, Shi-Young (Department of thoracic and cardiovascular surgery, Kuri Hospital, College of medicine, Hanyang University) ;
  • Jeon, Seok-Chol (Department of diagnostic radiology, College of medicine, Hanyang University) ;
  • Lee, Won-Mi (Department of pathology, College of medicine, Hanyang University) ;
  • Park, Chan-Kum (Department of pathology, College of medicine, Hanyang University)
  • 송동섭 (한양대학교 의과대학 흉부외과학 교실) ;
  • 지행옥 (한양대학교 의과대학 흉부외과학 교실) ;
  • 정원상 (한양대학교 의과대학 흉부외과학 교실) ;
  • 강정호 (한양대학교 의과대학 흉부외과학 교실) ;
  • 김영학 (한양대학교 의과대학 흉부외과학 교실) ;
  • 김혁 (한양대학교 의과대학 흉부외과학 교실) ;
  • 이철범 (한양대학교 의과대학 구리병원 흉부외과학 교실) ;
  • 함시영 (한양대학교 의과대학 구리병원 흉부외과학 교실) ;
  • 전석철 (한양대학교 의과대학 진단방사선과학 교실) ;
  • 이원미 (한양대학교 의과대학 병리학 교실) ;
  • 박찬금 (한양대학교 의과대학 병리학 교실)
  • Published : 2001.06.01
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Abstract

Langerhans\` Cell Histiocytosis(LCH) is a disease of unknown origin, characterized by abnormal proliferation of Langerhans\` cells. Previously, it has been called histiocytosis X, which included eosinophilic granuloma, Hand-Sch ller-Christian\`s disease, and Letterer-Siwe disease. Any organs or tissues such as skin, lymph nodes, bone and bone marrow can be involved. However, LCH of chest wall is rarely reported in our country. We experienced a 18 month old male child, who had osteolytic lesion involving the rib with axillary lymph node metastasis. The tumor was confirmed as LCH after surgery.

Langerhans 세포 조직구증(LCH, Langerhans\` Cell Histiocytosis)은 Langerhans\` cell histiocyte의 이상 증식을 특징으로 하는 원인 불명의 질환이다. 이 질환은 eosinophilic granuloma, Hand-Sch ller-Christian씨 병, Letterer-Siwe병을 포함하는 것으로 과거에는 histiocytosis X로 불리던 질환이다. 피부, 림프절, 골, 골수 및 체내 모든 조직과 기관을 침범할 수 있으나 국내에서 흉벽에서 발생된 예는 보고된 증례가 많지않다. 18개월 된 남자 환아에서 흉벽의 늑골에서 기원하여 골용해 소견을 동반한 종괴가 있어 수술적 절제한 후 LCH로 확진된 증례가 있어 문헌고찰과 함께 보고하는 바이다

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References

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