Biotechnology and Bioprocess Engineering:BBE

The Korean Society for Biotechnology and Bioengineering (한국생물공학회)
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Hibernation of Mammalian Cells at a Living Body Temperature

  • Hyon, Suong-Hyu (Institute for Frontier Medical Sciences, Kyoto University, Sakyo-ku, Kyoto 606-8507, Japan) ;
  • Kim, Do-Hoon (Institute for Frontier Medical Sciences, Kyoto University, Sakyo-ku, Kyoto 606-8507, Japan)
  • Published : 2001.07.01
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Abstract

The present study revealed that polyphenol induces the hibernation of mammalian cells at the living body temperature. It was found that polyphenol is a cytostatic sleeping agent for mam-malian cells, where almost all cells resume proliferation after the hibernation period and cell death seldom occurs. By changing the concentration for polyphenol, various mammalian cells can be stored under different conditions, such as temporary sleep, and hibernation condi-tions.

Keywords

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