Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Anesthetic Effects of Tiletamine/Zolazepam in Combination with Acepromazine or Fentanyl/Xylazine/Azaperone in Dogs

개에서 Tiletamine/Zolazepam 합제에 Acepromazine 또는 Fentanyl/Xylazine/Azaperone 합제의 병용투여시 마취효과

  • 이성림 (경상대학교 수의과대학·동물의학연구소) ;
  • 황재민 (경상대학교 수의과대학·동물의학연구소) ;
  • 연성찬 (경상대학교 수의과대학·동물의학연구소) ;
  • 이효종 (경상대학교 수의과대학·동물의학연구소)
  • Published : 2001.03.01
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Abstract

A combined anesthesia in terms of balanced anesthesia has been widely used for enhancement of anesthetic potency, decrement of dosage, reduction of side effects and better muscle relaxation. Recently, tiletamine/zolazepam (T/Z) has been widely used for the general anesthesia in dogs, but there have been few studies on balanced anesthesia of this drug in combination with other drugs. In this experiment, the combinations of T/Z with acepromazine or fentanyl/xylazine/azaperone (F/X/A) have been compared for the anesthetic effects in dogs. Healthy 5 mongrel dogs were allocated into three treatment groups ; Group Z (atropine + T/Z), Group A + Z (atropine/acepromazine + T/Z) in runs of 10 replication. The rapid induction of anesthesia was shown in all three treatment groups. The maintenance time of anesthesia was significanty increased to 101.4$\pm$6.2 minutes (44 min. more than that of group Z) in Group A + Z and 127.4$\pm$4.7 minutes (70 min. more than that of group Z) in Group F + Z, respectively. The recovery from anesthesia was rapid in Group F + Z. In blood analysis, there was no significant variation in three groups but hyperglycemia in Group F + Z. These results indicate that the balanced anesthesia of T/Z with F/X/A was superior to other two methods for maintaining and recovering from the anesthesia, and could be applied for general anesthesia in dogs.

Keywords

References

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