Journal of the East Asian Society of Dietary Life (동아시아식생활학회지)

The East Asian Society of Dietary Life (동아시아식생활학회)
권호 표지

Recent Research Trend on Free Radical Scavenger and Metallothioneins on Cadmium

Cadmium에 대한 Metallothionein 및 Free Radical Scavenger에 관한 최근의 연구 동향

  • Published : 2001.02.01
Download PDF
⟨ Previous Next ⟩

Abstract

Since the Industrial Revolution, people have enjoyed an abundant life, owing to the technological innovations of science. However, because of changes in the environment or polution to the environment, it has brought on many chronic diseases. Especially, even though it may be a small amount, if cadmium gets into a human body, because its biological half life is long, it fatally causes a kidney disease and damage to human organisms. It was reported that Metallothioneins(MT), a substance that is closely related with a free radical that comes from environmental pollution and the course of which cadmium, which causes chronic addition in the body, is formed, along with harmful metals, make the toxicity reduce. MT compound led into the body by cadmium indirectly functions as an antioxidation, supplied adequate amount of vitamin E, and suppresses the accumulation of cadmium in heart, liver and blood. Cadmium content found in Korean soil according to the test conducted from 1992 to 1996 was 0.02~0.03mg/kg in cereals, pulses, and potatoes. Free radical scavenger, finding solution for metal substance that comes from environmental pollution from food and natural substances implicates a better future for the study of food science.

Keywords

References

  1. Nutrition and environment health, minerals and macro-nutrient v.2 Edward, J. C.
  2. Metal toxicity in mammals v.2 Venugopad, B.:Luckey, T. D.
  3. General Chemistry(Fifth Edition) James, E. B.
  4. Bull. Inst. Yamagata, N.;Iwashima, K.;Nagai, T.
  5. 17th Int. Congr. Occup. Health Tsuchiya, K.;Seki, Y.;Sugita, M.
  6. Fifth International Water Pollution Research Conference Relation between the Itai-itai disease and the pollution of river water by cadmume from a mine Koboyashi, J.
  7. Modge HC and Smith RP. Clinical toxicology of commercial products, Acute poisoning(Home and Farm) Gleason, M. N.;Gosselin, R. S.
  8. Korean J. Nutrition v.33 no.1 Effect of Vitamin E on Antioxidative Defense System of Liver in Acute Cadmium-Poisoned Rats Kim, K. P.;Rhee, S. J.
  9. Bull. Environ. Contam. Toxicol. v.54 Cadmium concentrations in human real cortex tissue(Necropsies) Artigues, L. M.;Camean, A.;Gonzalez, G.;Repetto, M.
  10. Environmental Research v.70 Uninary α₁-microglobulm, β₂-microglobulm, and retinol-binding Protein levelsin general populations in Japan with references to cadmium in urine, blood and 24-hour food duplicates Ikeda, M. C.;Moon, C. S.;Xhang, Z. W.;Iguchi, H. I.;Wanabe, T.;Iwami, O.Imaj, Y.Shimbo, S.
  11. J. Lab. &. Clin. Med. v.60 Variability in the metal conrent of human organs Perry, H. M.;Tipton, I. H.;Schroeder, H. A.;Cook, M. J.
  12. Food Hygiene Sawamura, R.;Hinda, S.;Asaths, H.
  13. The Report of National Institute of Environmental Research v.10 A Study on the natural contents of heavy metals in paddy soil and brown rice in Korea Rhu, H. I.;Suh, S. Y.;Jun, S. H.;Lee, M. H.;Yu, S. J.;Hur, S. N.;Kim, S. Y.
  14. Food Sanitation Research v.30 Notification Ministry of Health and Welfare(Japan)
  15. Field assessment of effects of dumping waters at sea v.72 Bucke, D.;Norton, M. G.;Rolfe, M. S.
  16. Environmental Health Criteria No. 143 Cadmium WHO
  17. Integrated criteria documents cadmium Ros, J. P. M.;Sloof, W.
  18. '95 National Nutrition Survey Report Ministry of Health and Welfare
  19. J. Korean Soc. Food Sci. Nutr. v.29 no.3 Trace metal contents in cereals, pulses and potatoes and their safety evaluations Kim, M. H.;Chang, M. I.;Chung, S. Y.;Sho, Y. S.;Hong, M. K.
  20. J. Korean Soc. Food Sci. Nutr. v.29 no.2 Effect of methanol extracts of black soybean on enzymes activities of serum in rats fed Pb and Cd solution Han, S. H.;Shin, M. K.;Kim, Y. W.;Lim, S. J.
  21. Nipponkagakukai Cadmium Yamaken, N.
  22. J. Amchen. Soc. v.79 Margoshes, K.;Vallee, B. L.
  23. Free radicals in biology and medicine Barry, H.;John M. C. Gutteridge
  24. J. Inst. Nat. Sci. v.10 Toxicity of Cadmium Yu, T. S.
  25. Toxicol. Appl. Phamacol. v.107 no.69 Gastrointestinal absorption of cadmium and metallothionein Ohta, H.;Cherian M.
  26. Toxicol. Appl. Phamacol. v.117 no.70 Accumulation and degradation of protein moiety of Cd-MT in the mouse kidney Dorian, C.;Gatto, V. H.;Gattone, E.;Klassenm, C. D.
  27. J. Nutr. v.118 Role of copper in the regulation and accumulation of superoxide dismutase and metallothionein in rat liver Keun, C.;Nadia, R.;Don, T.;Carl. L. K.;Kenjie, A.;Robert, R.
  28. Fed. Proc. v.43 Characterization of a labile intracellular zinc pool and its hepatocytes Pattison, S. E.;Cousins, R. J.
  29. Am. J. Clin. Nutr. v.53 Antioxidant nutrients and disease prevention: an overview Diplock, A. T.
  30. Arch. Biochem. Biophys v.158 Superoxide dismutase : A comparison of rate constants Forman, H. J.;Fridovich, I.
  31. J. Pharmacol. Exp. Ther. v.227 Plasma Glutathione and glutathione disulfied in the rat : Regulation and response to oxidative stres. Adams, J. D.;Lauerburg, B. H.;Mitchell, J. R.
  32. The third International Green Tea Symposium Presentation Papers v.67 Heavy metal exclusion and detoxification of Korean green tea, woolong tea and tea Lee, S. J.;Kim, M. J.;Youn, Y. H.
  33. J. Nutr. v.125 Cancer prevention by soy products Kenny, A.
  34. J. Nutr. v.125 Soybean phytoestrongen intake and cancer risk Adlercreutz. H.;Goldim, B. R.;Gorbach, S. L.;Hockerstedt, K. A. V.;Watanabe, S.;Hamalainen, E. K.;Wahala, K. T.;Hase, T. A.;Fotsis, T.
  35. Korean J. Nutrition v.31 no.4 Retarding Effect of Dietary Fibers Isolated from Persimmon Peels and Jujubes on in vitro Glucose, Bile Acid and Cadmium Transport Lee. H. J.;Kim, M. K.
  36. Envoron. Health Perspect. v.54 Dietary protein effects on cadmium and metallothionein accumulation in the liver and kidney of rats Revis, N. W.;Osbome, T. R.
  37. The effects dietary zinc on cadmium toxicity and metabolism in rats Bae, K. H.
  38. Effects of dietary zinc on cadmium toxicity and metabolism in rats Bae, S. Y.
  39. Plant Foods for Human Nutrition v.49 no.4 in vitro mineral binding capacity of five fiber sources and their insoluble components for copper and zinc Claye, S. S.;Idouraine, A.;Weber, C. W.
  40. Acta. Pharmacol. Toxicol. v.59 no.7 Effects of dietary factors on G. I. Cd absorption in nice Schafer, L.;Anderson, O.;Nielsen, J. B.
  41. J. Nutr. v.122 Regulation of antioxidant enzymes Harris, E. D.
  42. Korean J. Nutrition v.32 no.4 Effect of Korean Native Plant Diet on Lipid Metabolism, Antioxidative Capacity and Cadmium Detoxification in Rats Park, J. A.;Kim, M. K.