Journal of Mechanical Science and Technology

The Korean Society of Mechanical Engineers (대한기계학회)
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The Elastic Moduli and Fatigue Properties of Canine Trabecular Bone Tissue

  • Park, Kuiwon (Biomedical Research Center, Korea Institute of Science & Technology) ;
  • Gon Khang (School of Electronics & Information, Kyung Hee University) ;
  • Steven A. Goldstein (Orthopaedic Research Laboratories, The University of Michigan)
  • Published : 2001.07.01
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Abstract

The elastic modulus and fatigue properties of canine and human trabecular bone tissues (single trabecular) were experimentally determined on a microstructural level using four-point bending cyclic test, and they were compared based on microstructural characteristics and mineral density. The results showed that canine trabecular bone tissue had significantly lower modulus and lower fatigue strength than human tissue. The observed microstructural differences between the two tissues may be more responsible for the differences, although the lower mineral density in canine tissue might also have contributed to the lower modulus and fatigue strength.

Keywords

References

  1. Bobyn, J. D., Pilliar, R. M., Cameron, H. U. and Weatherly, G. C, 1980, 'The Optimum pore size for the Fixation of Porous Surfaced Metal Implants by the Ingrowth of Bone.' Clin. Orthop. Rel. Res, Vol, 150, pp. 263-270
  2. Bos, G. D., Goldberg, V. M., Powell, A. E., Heiple, K. G. and Zika, J. M, 1983, 'The Effects of Histocompatibility Matching on Canine Frozen Bone Allografts,' J. Bone Jt Surg, Vol, 65A, pp. 89-96
  3. Burr, D. B., Martin, R. B., Schaffler, M. B. and Radin, E. L., 1985, 'Bone Remodeling in Response to in Vivo Fatigue Damage,' J. Biomechanics, Vol, 18, pp. 189-197 https://doi.org/10.1016/0021-9290(85)90204-0
  4. Burr, D. B., Schaffler, M. B. and Frederickson, R. G., 1988, 'Composition of the Cement Line and its Possible Mechanical Role as a Local Interface in Human in Compact Bone,' J. Biomechanics, Vol, 21, pp. 939-945 https://doi.org/10.1016/0021-9290(88)90132-7
  5. Carter, D. R., Hayes, W. C. and Schurman, D. J., 1976, 'Fatigue Life of Compact Bone-II. Effects of Microstructure and Density,' J. Biomechanics, Vol, 13, pp. 27-38
  6. Carter, D. R. and Hayes, W. C, 1977, 'The Compressive Behavior of Bone as a Two-Phase Porous Structure,' J. Bone Jt Surg, Vol, 59A, pp. 954-962
  7. Carter, D. R., Caler, W. E., Spengler, D. 51. and Frankel, V. H., 1981, 'Uniaxial Fatigue of Human Cortical Bone: The Influence of Tissue Physical Characteristics,' J. Biomechanics, Vol, 14, pp. 461-470 https://doi.org/10.1016/0021-9290(81)90096-8
  8. Choi, K. and Goldstein, S. A., 1992, 'A Comparison of the Fatigue Behavior of Human Trabecular and Cortical Bone,' J. Biomechanics, Vol, 25, pp. 1371-1381 https://doi.org/10.1016/0021-9290(92)90051-2
  9. Choi, K., Kuhn, J. L., Ciarelli, M. J. and Goldstein, S. A., 1990, 'The Elastic Moduli of Human Subchondral, Trabecular, and Cortical Bone Tissue and the Size-Dependency of Cortical Bone Modulus,' J. Biomechanics, Vol, 23, pp. 1103-1113 https://doi.org/10.1016/0021-9290(90)90003-L
  10. Ciarelli, M. J., Goldstein, S. A., Kuhn, J. L., Cody, D. D. and Brown, M. B., 1991, 'The Orthogonal Mechanical Properties and Density of Human Trabecular Bone from the Major Metaphyseal Regions Utilizing Materials Testing and Computed Tomography,' J. Orthop. Res, (accepted)
  11. Currey, J. D., 1969, 'The Relationship Between the Stiffness and the Mineral Content of Bone,' J. Biomechanics, Vol, 2, pp. 477-480 https://doi.org/10.1016/0021-9290(69)90023-2
  12. Dannucci, G. A., Martin, R. B. and Patterson -Buckendahl, P. , 1987, 'Ovarectomy and Trabecular Bone Remodeling in the Dog,' Calcif. Tissue Int, Vol, 40, pp. 194-199 https://doi.org/10.1007/BF02556621
  13. Darby, A. J. and Meunier, P. J., 1981, 'Mean Wall Thickness and Formation Periods of Trabecular Bone Packets in Idiopathic Osteoporosis,' Calcif. Tissue Int, Vol, 33, pp. 199-204 https://doi.org/10.1007/BF02409438
  14. Ducheynne, P., Heymans, L., Martens, M., Aernoudt, F., De Meester, P. and Mulier, J. C, 1977, 'The Mechanical Behavior of Intracondylar Cancellous Bone of the Femur at Different Loading Rates,' J. Biomechanics, Vol, 10, pp. 747 -762 https://doi.org/10.1016/0021-9290(77)90089-6
  15. Enneking, W. F., Burchardt, H., Paul, J. J. and Piotrowsu, G., 1975, 'Physical and Biological Aspects of Repair in Dog Cortical Bone Transplants,' J. Bone Jt Surg, Vol, 57A, pp. 237-252
  16. Faugere, M. C, Rush, M., Fiedler, R. M. and Malluche, H. H., 1985, 'Loss of Ovarian Function Causes Bone Loss Due to an Osteoblastic Deficiency on Dogs,' Clin. Research, Vol, 33, 849A
  17. Frost, H. M., 1969, 'Tetracycline-Based Histological Analysis of Bone Remodeling,' Calc. Tiss. Res, Vol, 3, pp. 211-237 https://doi.org/10.1007/BF02058664
  18. Goldstein, S. A., Matthews, L. S., Kuhn, J. L., and Hollister, S. J., 1990, 'Trabecular Bone Remodeling: An Experimental Model,' J. Biomechanics (submitted)
  19. Gong, J. R., Arnold, J. S. and Cohn, S. H., 1964, 'Composition of Trabecular and Cortical Bone,' Anat. Rec. Vol, 149, pp. 325-331 https://doi.org/10.1002/ar.1091490303
  20. Eiarris, W. H., Heaney, R. P., Jowsey, J., Cockin, J., Akins, C., Graham, J. and Weinberg, E. H., 1972, 'Growth Hormone: the Effects on Skeletal Renewal in the Adult Dog., I. Morphometic Studies,' Calc. Tiss. Res, Vol, 10, pp. 1-13 https://doi.org/10.1007/BF02012530
  21. Hollister, S. J., Fyhrie, D. P., Jepsen, K. J. and Goldstein, S. A., 1990, 'Application of Homogen-ization Theory to the Study of Trabecular Bone Mechanics,' J. Biomechanics, (accepted)
  22. Keiler, T. S., Lovin, J. D., Spengler, D. M. and Carter, D. R., 1985, 'Fatigue of Immature Baboon Cortical Bone,' J. Biomechanics, Vol, 18, pp. 297-304 https://doi.org/10.1016/0021-9290(85)90847-4
  23. Kuhn, J. L., Goldstein, S. A., Choi, K., London, M., Feldkamp, L. A. and Nlattltews, L. S., 1989a, 'A Comparison of the Trabecular and Cortical Tissue Moduli from Human Iliac Crests,' J. Orthop. Res, Vol, 7, pp. 874-886 https://doi.org/10.1002/jor.1100070614
  24. Kuhn, J. L., Goldstein, S. A., Ciarelli, M. J. and Matthews, L. S., 1989b, 'The Limitations of Canine Trabecular Bone as a Model for Human: A Biomechanical Study,' J. Biomechanics, Vol, 22, pp. 95-107 https://doi.org/10.1016/0021-9290(89)90032-8
  25. Martin, R. D., Albright, J. P., Jee, W. S. S., Taylor, G. N. and Clarke, W. P., 1981, 'Bone Loss in the Beagle Tibia: Influence of Age, Weight, and Sex,' Calcif. Tissue Int, Vol, 33, pp. 233-238 https://doi.org/10.1007/BF02409442
  26. Mather, B. S., 1968, 'The Effects of Variation in Specific Gravity and Ash Content on the Mechanical Properties of Human Compact Bone,' J. Biomechanics, Vol, 1, pp. 207-210 https://doi.org/10.1016/0021-9290(68)90005-5
  27. Pedersen, D. R., Brown, T. D. and Brand, R. A., 1990, 'Bone Ingrowth Stress Distributions Within a Novel Prosthesis Anchorage Laser,' Trans. 36th Orthop. Res. Soc, 15,205
  28. Schaffler, M. B. and Burr, D. B., 1987, 'Morphology of the Osteonal Cement Line in Human Bone,' Anat. Rec, Vol, 217, pp. 223-228 https://doi.org/10.1002/ar.1092170302
  29. Schaffler, M. B. and Burr, D. B., 1988, 'Stiffness of Compact Bone: The Effects of Porosity and Density,' J. Biomechanics, Vol, 21, pp. 13-16
  30. Snow, G. R. and Anderson, C. , 1986, 'The Effects of 17-Estradiol and Progestagen on Trabecular Bone Remodeling in Oophorectomized Dogs,' Calcif. Tissue Int, Vol, 39, pp. 198-205 https://doi.org/10.1007/BF02555118
  31. Snow, G. R, Cook, M. A. and Anderson, C, 1984, 'Oophorectomy and Conical Bone Remodeling in the Beagle,' Calcif. Tissue Int, Vol, 36, pp. 586-590
  32. Swanson, S. A. V., Freeman, M. A. R. and Day, W. H., 1971, 'The Fatigue Properties of Human Cortical Bone.' Med. & Biol. Engng, Vol, 9, pp. 23-32 https://doi.org/10.1007/BF02474401
  33. Vahey. J. W., Lewis, J. L. and Vanderby, R. Jr., 1987, 'Elastic Moduli, Yield Stress, and Ultimate Stress of Cancellous Bone in the Canine Proximal Femur.' J. Biomechanics, Vol, 20, pp. 29-34 https://doi.org/10.1016/0021-9290(87)90264-8