KSBB Journal

The Korean Society for Biotechnology and Bioengineering (한국생물공학회)
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Directed Evolution in Protein Functionality Improvement

단백질 기능 향상을 위한 방향적 진화

  • 강환구 (한남대학교 화학공학과 생물화공실험실) ;
  • 김학성 (한국과학기술원 생물과학과 생물화학공학 연구실)
  • Published : 2001.04.01
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Abstract

The dynamic evolution process has resulted in the myriad shapes, functions, and systems evident in every living organism. For centuries, people have been harnessing the power of evolution to produce new varieties of plants and animals, such as producing tomatoes from berries and Chihuahuas from wolves. Now scientists are using it to produce better molecules, ranging from drugs to industrial chemicals, and doing it in days or weeks rather than eons. The ingenious process, which creates genetic diversity and selects those with desired features in the laboratory, is called directed evolution or test tube evolution. In this paper, concepts of directed molecular evolution and some examples will be discussed.

Keywords

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