KSBB Journal

The Korean Society for Biotechnology and Bioengineering (한국생물공학회)
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Enzymatic Glycosylation of Acrylic Acid and Methacrylic Acid

아크릴산과 메타크릴산의 효소적 배당화

  • Published : 2001.02.01
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Abstract

Glyco-acrylate and methacrylate were synthesized by lipase-catalyzed glycosylation of acrylic acid, methacrylic acid and their vinyl esters with $\beta$-methyl fructoside and glycerol in t-butanol as a reaction medium. At the optimum conditions for enzymatic glycosylation of acrylic acid and vinyl methacrylate, we attained up to 80% conversion for glyco-acrylate from acrylic acid and 90% conversion for glyco-methacrylate from vinyl methacrylate. The polymerizable glyco-acrylates and methacrylate have biomedical application as hydrophilic monomers and hydration modifiers to be use for hydrogel contact lens formulation.

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