마전자약침(馬錢子藥鍼)이 Adjuvant 관절염(關節炎)에 미치는 영향(影響)에 관한 실험적(實驗的) 연구(硏究)

Effect of Strychni Semen Aqua - acupuncture in Rats with Arthritis induced by Freund's Complete Adjuvant

  • 배철우 (경원대학교 한의과대학 침구학교실) ;
  • 김기현 (경원대학교 한의과대학 침구학교실) ;
  • 황현서 (경원대학교 한의과대학 침구학교실) ;
  • 김연섭 (경원대학교 한의과대학 해부경혈학교실)
  • Bae, Chul-Woo (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung-Won University) ;
  • Kim, Kee-Hyun (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung-Won University) ;
  • Hwang, Hyeun-Seo (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung-Won University) ;
  • Kim, Youn-Sub (Department of Anatomy & Meridianology, College of Oriental Medicine, Kyung-Won University)
  • 투고 : 2001.01.10
  • 심사 : 2001.01.17
  • 발행 : 2001.02.20

초록

Objectives and Mtthods : In order to study on the Effect of Strychni Semen aqua-acupuncture on the arthritis induced by injecting Freund's complete adjuvant to the right posterior planta of rat's foot, rats were divided 5 groups equally, one group was not treated(Normal) and the other groups were induced arthritis by injecting Freund's complete adjuvant(Control, ST, SS, SST). Control was not treated after injecting of Freund's complete adjuvant. ST was 0.2cc Saline-injected Group at Chok-Samni(ST36) either days during 2 weeks after injecting of Freund's complete adjuvant. SS was 0.2cc Strychni Semen-subcutaneous injected group either days during 2 weeks after injecting of Freund's complete adjuvant. SST was 0.2cc Strychni Semen-injected group at Chok-Samni(ST36) either days during 2 week after injecting of Freund's complete adjuvant. And then effect of Strychni Semen aqua-acupuncture on the edema, numbers of blood WBC, platelet, hematocrit, contented quantities of total protein, albumin in rats with F.C.A were measured. Results : The following results have been obtained. 1. In effect of Strychni Semen aqua-acupuncture on plantar edema, SS showed significant decrease compared with control. 2. In effect of Strychni Semen aqua-acupuncture on WBC, SS and SST showed significant decrease compated with control. 3. In effect of Strychni Semen aqua-acupuncture on platelet, SS and SST did not show significant decrease. 4. In effect of Strychni Semen aqua-acupuncture on hematocrit, SST showed significant increase compared with control. 5. In effect of Strychni Semen aqus-acupuncture on the contents quantity of total protein and albumin, SS showed significant increase compared with control: Conclusions : Accoring to this result, Strychni Semen aqua-acupunture inserted into Chok-Samn i(ST36) appeared to have effect on Adjuvant arthritis of rats. Therefore it is oxpected that Strychni Semen aqua-acupunture may be available clinically.

키워드

참고문헌

  1. 整形外科學 大韓整形外科學會
  2. 醫學入門(下卷) 李梃
  3. 痺證 權宰植(外 4人)
  4. 東醫寶鑑 許俊
  5. 舍岩道人鍼灸要訣 舍岩仙師(譯註)
  6. 丹溪心法附餘 龐廣
  7. 東垣十種醫書 李東垣
  8. 黃帝內經素問注證發微 馬蒔(編註)
  9. 鍼灸大成 楊繼洲
  10. 景岳全書(上) 張介賓
  11. 萬病回春 龔延賢
  12. 診療要鑑(上卷) 金定濟
  13. Clinical Immnuol Immunopathol v.73 Collagen - induced arthritis asa model of rheumatoid arthritis Durie, F.H.;fava, R.A.;Noelle, R.J.
  14. 醫藥情報誌 v.11 류마토이드 關節炎의 原因 및 病態生理 최영길
  15. 尙志大韓醫學碩師學位論文 牛膝藥鍼이 Rat의 Adjuvant 關節炎에 미치는 影響 張通榮
  16. 大田大韓醫學碩士學位論文 續斷藥鍼이 Adjuvant 關節炎에 미치는 影響 李煌烈
  17. 大田大韓醫學碩士學位論文 梔子藥鍼이 白鼠의 Adjuvant 關節炎에 미치는 影響 金洛賢
  18. 大田大韓醫學碩士學位論文 斑苗藥鍼이 白鼠의 Adjuvant 關節炎에 미치는 影響 李姸炅
  19. 慶熙大韓醫學碩士學位論文 加味疎風活血湯水鍼이 Adjuvant 關節炎에 미치는 影響 宋彦錫
  20. 慶山大韓醫學碩士學位論文 紅花藥鍼이 Adjuvant 關節炎에 미치는 影響에 관한 實驗的 硏究 李熙泰
  21. 暻園大韓醫學碩士學位論文 馬錢子가 쥐 骨格筋의 筋萎縮에 미치는 影響 宋榮商
  22. 本草學 全國韓醫科大學本草學敎授(編著)
  23. 鍼灸學(上) 全國韓醫科大學校 鍼灸經穴學敎室(編著)
  24. Arch. Int. Pharmacodyn. Rosenthale, M.E.
  25. 臨床檢査法提要(27 ed.) 舍井泉(外)
  26. Textbook of clinical chemistry Norbert, W.T.
  27. 鍼灸學(下) 全國韓醫科大學校 鍼灸經穴學敎室(編著)
  28. 金匱要略方論 張仲景
  29. 諸病源候論 巢元方
  30. 普濟方 朱橚
  31. 丹溪心法附餘 朱震亨
  32. 奇蹟의 藥鍼療法 金延彦
  33. Drig Exp.Clin. Res v.17 no.10/11 Immunosuperssive sctivity of 15-deo-xyspergualin (15-DOS) on various medels of rheumatoid arthritis. Schorlemmer, H.U.;Bartlett, R.R.;Schleyerbach, R.;Seiler, F.R.
  34. Res. Exp. Med. v.197 Methotrexate suppresses nitric oxide production ex vivo in macrophages from rats with adjuvant-induced arthritis. Omata T.;Segawa Y.;Inoue N.;Tsuzulike N;Itokazu Y.;Tamaki H.
  35. 本草綱目 李時珍
  36. 臨床病理學 大韓臨床病理學會
  37. 臨床病理檢査 이삼열
  38. 血液學實技 安富浩
  39. 病理學 大韓病理學會