Childhood Kidney Diseases

Korean Society of Pediatric Nephrology (대한소아신장학회)
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A Case of Lupus Nephritis with Positive Antiphospholipid Antibodies, Initially Detected Through Analysis of Urinary Mass Screening

학교신체검사에서 발견된 항인지질 항체 양성 낭창성 신염 1례

  • Lee Taek-Jin (Departments of Pediatrics, The Institute of Kidney Disease, Yonsei University College of Medicine) ;
  • Choi Min Sook (Departments of Pediatrics, The Institute of Kidney Disease, Yonsei University College of Medicine) ;
  • Lee Young-Mock (Departments of Pediatrics, The Institute of Kidney Disease, Yonsei University College of Medicine) ;
  • Kim Ji-Hong (Departments of Pediatrics, The Institute of Kidney Disease, Yonsei University College of Medicine) ;
  • Kim Pyung-Kil (Departments of Pediatrics, The Institute of Kidney Disease, Yonsei University College of Medicine) ;
  • Jeong Hyeon-Joo (Departments of Pathology, The Institute of Kidney Disease, Yonsei University College of Medicine)
  • 이택진 (연세대학교 의과대학 소아과학교실, 신장질환연구소) ;
  • 최민숙 (연세대학교 의과대학 소아과학교실, 신장질환연구소) ;
  • 이영목 (연세대학교 의과대학 소아과학교실, 신장질환연구소) ;
  • 김지홍 (연세대학교 의과대학 소아과학교실, 신장질환연구소) ;
  • 김병길 (연세대학교 의과대학 소아과학교실, 신장질환연구소) ;
  • 정현주 (연세대학교 의과대학 병리학교실, 신장질환연구소)
  • Published : 2001.10.01
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Abstract

Antiphospholipid syndrome is a thrombotic disorder characterized by the association of arterial and venous thrombosis with the antibodies directed toward phospholipids. The presence of these antibodies in systemic lupus erythematosus(SLE) has been shown to be related to several clinical and analytical alterations. We experienced one case of lupus nephritis with positive antiphospholipid antibodies in a 10-year-old girl whose chief complaint was persistent microscopic hematuria. We report this case with a brief review of related literatures. (J. Korean Soc Pediatr Nephrol 2001 ;5 : 219-24)

저자들은 전신성 홍반성 낭창의 특이적인 증상 없이 학교 신체검사중 우연히 발견된 현미경적 혈뇨를 주소로 내원하여 시행한 혈액응고검사(prothrombin time, partial thromboplastin time)와 루푸스 항응고인자 (lupus anticoagulant, LA), cardiolipin에 대한 항체(anticardiolipin antibody, aCL) 검사에서 항인지질증후군으로 진단된 10세 여자 환아에서 신조직 검사를 시행하여 확진한 낭창성 신염 1례를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

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