Effects on the secretion of Gastrin and Uropepsin of rats treated with Coptidis Rhizoma, Scutellariae Radix and Phellodendri Cortex

황련 황금 황백이 백서의 GASTRIN 및 UROPEPSIN 분비에 미치는 영향

  • 김성욱 (상지대학교 부속 한방병원) ;
  • 김병우 (상지대학교 부속 한방병원)
  • Published : 2001.12.30

Abstract

Each decoction of Coptidis Rhizoma, Scutellariae Radix and Phellodendri Cortex was orally administrated to the rates. And the effects on the Gastrin and Uropepsin secretions were observed. The results were as follows: 1. The effects on the secretio of Gastrin in the experimental groups administrered each with Coptidis Rhizoma and Scutellariae Radix comparing with the normal group, showed signficant values P<0.05, P<0.02, P<0.01 and P<0.001 separately. However the group medicated with Phellodendri Cortex showed significant values only 30 minutes after the administration. 2. Uropepsion level in the experimental group administered each with Coptidis Rhizoma and Phellodendri Cortex, comparing with the normal group, showed highly significant statistic values (P<0.001). Another experimental group medicated with Scutellariae Radix showed significantly statistical values (P<0.001) 240 minutes after the administration. 3. According to the above mentioned results it was onculuded tat the secretion of Gastrin in plasma and Uropepsin content of urine in albino rats treated with Coptiodis Rhizoma decoction were remarkaby increased as comparing with Scutellariae Radix and Phellodendri Cortex decoction.

Keywords

References

  1. 藥品資源植物學 金永在;金一赫;柳庚秀;李永魯
  2. 生理學 김철;남기용;신동훈
  3. 申氏 本草學 申佶求
  4. 脾系內科 柳基遠
  5. 內科學 李文鎬;金鍾勳;許仁穆
  6. 本草學 李尙仁
  7. 大韓藥理學會雜誌 v.12 黃連成分의 血壓下降作用 곽인숙;이상복;조병헌;조규철
  8. 平胃散 投與가 家兎의 胃液中 HCI및 Pepsin에 미치는 影響에 關한 硏究 柳逢夏
  9. 中藥大辭典 江蘇新醫學院(編)
  10. 中藥新編(편저) 兵晨波
  11. 東洋醫學大辭典 謝觀
  12. 中草約學(편저) 上海中醫學院(編)
  13. 徐靈胎醫書 三十二種 徐靈胎
  14. 中國藥物學 時逸人
  15. 新農本草經 v.上 吳普
  16. 新農本草經 v.中 吳普
  17. 本草從新 吳義洛
  18. 六科準繩 女科 王肯當
  19. 本草備要 王昻
  20. 本草綱目 李時珍
  21. 臨床 檢査法 提要 金井泉;金井正光
  22. 岐阜醫科大學記要 v.6 態岐平藏
  23. 日本 藥學雜誌 v.82 黃連의 鎭痙作用 原田正敏;萩庭丈壽
  24. 日本藥局方 日本厚生省
  25. 京都?立醫大誌 v.13 在藤一二
  26. Gastroenterology v.54 Immunochemical studies with synthetic human gastrin Mc Guigan, J.E.
  27. A maual of pharmacology and its application to therapeuitcs and toxicology Torald Sollman, M.D.
  28. Radioimmunoassay of Gastrin Gastroenterology v.58 Yalow, R.S.;Berson, S.A.