The Feasibility and Safety of Herbal Medication on Short Stature

성장치료를 위한 한약투여의 임상적 효과 및 안전성 평가

  • Cheong, Jeong-Ook (Department of Internal Medicine, Pundang CHA Oriental Hospital) ;
  • Yang, Tae-Kyu (Department of Internal Medicine, Pundang CHA Oriental Hospital) ;
  • Koo, Bon-Hong (Department of Internal Medicine, Kangnam CHA Oriental Hospital) ;
  • Lee, Sea-Yun (Department of Internal Medicine, Pundang CHA Oriental Hospital)
  • 정정욱 (분당차한방병원 한방내과) ;
  • 양태규 (분당차한방병원 한방내과) ;
  • 구본홍 (강남차한방병원 한방내과) ;
  • 이세연 (분당차한방병원 한방내과)
  • Published : 2001.12.30

Abstract

Objective : Recently many studies of herbal medication to promote growth have been implemented. The purpose of this study was to identify the feasibility and safety of herbal medication on short stature. Methods : 143 patients(87 males, 56 Females)who visited with short stature at Kangnam CHA Oriental Hospital From February 1999 to January 2000 and were treated during 6 months, were available for this study. We treated with 5 herbal medications.(Soeumin hyangbujapalmultang-gagambang, Soyangin yukmijihwangtang-gagambang, Taeumin chungsimyunjatang-gagambang, Boa-tang, Boikyangwi tang) At the begining of the treatment and after 6 months treatment, We measured height, weight and body mass index(BMI). And we investigated changes of aspartate aminotransferase(AST), alanine aminotransferase(ALT), blood urea nitrogen(BUN), alkaline phosphatase(ALP), creatinine. Results: The distribution of ages was from 5 years old to 17 years old. After herbal treatment, mean height, mean weight, mean BMI and mean percentile grade increased $138.5{\pm}15.6$ to $141.9{\pm}15.1$, from $36.9{\pm}13.2$ to $38.9{\pm}13.2$, from $18.5{\pm}3.29$ to $18.7{\pm}3.21$, from $3.2{\pm}1.2$ to $3.4{\pm}1.2$. The contents of AST, ALT, BUN, ALP and Creatinine were not showed any significant change. Conclusions : In the results We recognized Short stature was showed prominent feasibility and safety of herbal medication. Herbal Medication in patients with short stature will improve height velocity without liver and kidney function disorders.

Keywords

References

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