대한한방내과학회지 (The Journal of Internal Korean Medicine)

대한한방내과학회 (The Society of Internal Korean Medicine)
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한약 투여후 발생한 급성담즙정체성(약제유인성)간염 치험 1례

One Case Report of Acute Cholestatic-Hepatitis(Drug Induced Hepatitis) After Taking Herbal-Medicine

  • 이지연 (원광대학교 한의과대학 전주한방병원 내과) ;
  • 김관식 (원광대학교 한의과대학 전주한방병원 내과) ;
  • 정용준 (원광대학교 한의과대학 전주한방병원 내과) ;
  • 김형균 (원광대학교 한의과대학 전주한방병원 내과) ;
  • 이언정 (원광대학교 한의과대학 전주한방병원 내과) ;
  • 최우정 (원광대학교 한의과대학 전주한방병원 내과) ;
  • 한상칠 (원광대학교 한의과대학 전주한방병원 내과) ;
  • 오명진 (원광대학교 한의과대학 전주한방병원 내과) ;
  • 오로사 (원광대학교 한의과대학 전주한방병원 내과) ;
  • 양재훈 (원광대학교 한의과대학 전주한방병원 내과)
  • Lee, Ji-Youn (Department of Internal Medicine, Wonkwang University of Oriental, Medicine) ;
  • Kim, Kwan-Sik (Department of Internal Medicine, Wonkwang University of Oriental, Medicine) ;
  • Jeong, Yong-Jun (Department of Internal Medicine, Wonkwang University of Oriental, Medicine) ;
  • Kim, Hyung-Kuen (Department of Internal Medicine, Wonkwang University of Oriental, Medicine) ;
  • Lee, Eon-Jeong (Department of Internal Medicine, Wonkwang University of Oriental, Medicine) ;
  • Choi, Woo-Jung (Department of Internal Medicine, Wonkwang University of Oriental, Medicine) ;
  • Han, Sang-Chil (Department of Internal Medicine, Wonkwang University of Oriental, Medicine) ;
  • O, Moung-Jin (Department of Internal Medicine, Wonkwang University of Oriental, Medicine) ;
  • O, Ro-Sa (Department of Internal Medicine, Wonkwang University of Oriental, Medicine) ;
  • Yang, Jae-Hoon (Department of Internal Medicine, Wonkwang University of Oriental, Medicine)
  • 발행 : 2001.06.30
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초록

In western medicine, there are some reports about herbal medicine induced hepatitis, but in oriental medicine, there are few reports about that. We experienced one case of drug acute cholestatic-hepatitis in the treatment of oriental medicine for HNP. We treated the patient with acupuncture, physical therapy and herb medicine. The patient's symptoms improved after two weeks of treatment. In the course of treatment, the patient intermittently complained of general weakness, nausea, yellowish urin, dyspepsia, and abdominal discomfort. We recognized that total bilirubin(7.2mg/dl), direct bilirubin(5.5mg/dl), serum transaminase(AST 360U/L, ALT 354U/L), alkaline phosphatase(16.6 K/A), urobilinogen(++) and bilirubin(++) were elevated. We diagnosed drug induced hepatitis. We stopped giving herb medicine and began giving Saeng gan gunbi-tang and Injin-oryung-san. Saeng gan gunbi-tang and Injin-oryung-san have been used to treat hepatic disease and have been known to have beneficial effects. After 3weeks on medication, the clinical symptoms and liver function improved. So, we report this case to bring more attention to the safety and toxicity of herbal medicine.

키워드

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