Herbal Formula Science (대한한의학방제학회지)

The Korean Medicine Society for the Herbal Formula Study (대한한의학방제학회)
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Effect of Korean Carthami Semen and Estradiol-Carthami Semen On Osteoporosis In Ovariectomized Rats

국산홍화자(國産紅花子) 및 국산홍화자(國産紅花子)와 estradiol 병용투여가 난소적출로 유발된 흰쥐의 골다공증에 미치는 영향

  • Kim, Jong-Hun (College of Oriental Medicine, Kyungsan University) ;
  • Kim, Mi-Ryo (College of Oriental Medicine, Kyungsan University) ;
  • Byun, Bu-Hyung (College of Oriental Medicine, Kyungsan University) ;
  • Park, Ji-Ha (College of Oriental Medicine, Kyungsan University) ;
  • Kim, Jong-Dae (College of Oriental Medicine, Kyungsan University) ;
  • Lee, Eun-Sook (College of Oriental Medicine, Kyungsan University) ;
  • Seo, Bu-Il (College of Oriental Medicine, Kyungsan University)
  • 김종헌 (경산대학교 한의과대학) ;
  • 김미려 (경산대학교 한의과대학) ;
  • 변부형 (경산대학교 한의과대학) ;
  • 박지하 (경산대학교 한의과대학) ;
  • 김종대 (경산대학교 한의과대학) ;
  • 이은숙 (경산대학교 한의과대학) ;
  • 서부일 (경산대학교 한의과대학)
  • Published : 2001.12.20
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Abstract

Objective: The present study has been undertaken to investigate the effects of Korean Carthami Semen and Estradiol-Carthami Semen co-treatment on osteoporosis in ovariectomized rats. Method: In this experiment, the rats were ovariectomized. Rats were administered 3 kinds of medicine, Korean Carthami Semen, Estradiol, and Estradiol-Carthami Semen, which were taken orally. The levels of bone mineral density, osteocalcin, estradiol, ALP, phosphorus, calcium in serum, deoxypyridinoline in urine, calcium, phosphorus, ash weight of bone, body weight and uterus weight were measured. Results: These experimetal results, it appears that the only Carthami Semen have more less efficacy on osteoporosis but $E_2$-Carthami Semen co-treated group showed more effective on osteoporosis. Conclusions: Further west-east medicine combination study should be conducted to illustrate in depth the curing osteoporosis.

Keywords

References

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