Journal of Acupuncture Research

Korean Acupuncture & Moxibustion Medicine Society (대한침구의학회)
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Effects of Electroacupuncture on Neuropathic pain in Rats

신경병증성 통증에 대한 전침자극 효과의 연구

  • Hwang Byung-Gil (Department of East-West Medicine, Graduate School, Kyung-Hee University) ;
  • Yu Gi-Yong (Department of East-West Medicine, Graduate School, Kyung-Hee University) ;
  • Kim Ji-Hoon (Department of East-West Medicine, Graduate School, Kyung-Hee University) ;
  • Park Dong-Suk (Department of Acupuncture & Moxibution, College of Oriental Medicine, Kyung-Hee University) ;
  • Min Byung-Il (Department of East-West Medicine, Graduate School, Kyung-Hee University)
  • 황병길 (경희대학교 대학원 학과간협동과정 동서의학과) ;
  • 유기용 (경희대학교 대학원 학과간협동과정 동서의학과) ;
  • 김지훈 (경희대학교 대학원 학과간협동과정 동서의학과) ;
  • 박동석 (경희대학교 한의과대학 침구학교실) ;
  • 민병일 (경희대학교 대학원 학과간협동과정 동서의학과)
  • Published : 2001.12.20
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Abstract

Objcetive : Neuropathic pain sometimes arises from a partial peripheral nerve injury. This kind of pain is usually accompanied by spontaneous burning pain, allodynia and hyperalgesia. It has been well known that acupuncture is effective to the pain control from ancient time in Asia. However, it is not clear whether acupuncture can control neuropathic pain. The aim of the present study is to examine if acupuncture stimulation may be effective to the mechanical allodynia in a rat model of neuropathic pain. Methods : To produce neuropathic pain, under sodium pentobarbital anesthesia, the right superior caudal trunk was resected between the S3 and S4 spinal nerves. After the neuropathic surgery, we examined if the animals exhibited the behavioral signs of mechanical allodynia. The mechanical allodynia was assessed by stimulating the tail with von Frey hair (bending force : 2.0g). three or 6 weeks after the neuropathic surgery, acupuncture stimulation was delivered to Houxi (SI 3) as the following parameters (2HZ frequency, 0.07mA intensity and 3msec duration) for 30 minutes. Results : The stimulation of Houxi (SI 3) acupoint relieved the behavioral signs of mechanical allodynia. Conclusion : Our results suggest that acupuncture can control the mechanical allodynia of neuropathic pain.

Keywords

References

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