Journal of the Korean Association of Oral and Maxillofacial Surgeons
- Volume 27 Issue 5
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- Pages.404-416
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- 2001
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- 2234-7550(pISSN)
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- 2234-5930(eISSN)
HISTOLOGICAL CHANGES IN THE ELONGATED BONE AFFECTED BY OSTEODISTRACTION OF THE MANDIBLE IN THE DOG
성견 하악골 절단 후 기계적 골 견인에 의해 형성된 골 신장부에 대한 시기별 조직학적 변화
- Baek, Sun-Ho (Department of Oral & Maxillofacial Surgery, College of Medicine, Hallym University) ;
- Ahn, Byoung-Keun (Department of Oral & Maxillofacial Surgery, College of Medicine, Hallym University) ;
- Park, Young-Ju (Department of Oral & Maxillofacial Surgery, College of Medicine, Hallym University) ;
- Park, Hee-Geon (Department of Oral & Maxillofacial Surgery, College of Medicine, Hallym University) ;
- Park, Jun-Woo (Department of Oral & Maxillofacial Surgery, College of Medicine, Hallym University) ;
- Rhee, Gun-Joo (Department of Oral & Maxillofacial Surgery, College of Medicine, Hallym University) ;
- Lee, Yong-Chan (Department of Oral & Maxillofacial Surgery, College of Medicine, Hallym University) ;
- Cho, Byoung-Ouck (Department of Oral & Maxillofacial Surgery, College of Medicine, Hallym University)
- 백선호 (한림대학교 의과대학 치과학교실 구강악안면외과) ;
- 안병근 (한림대학교 의과대학 치과학교실 구강악안면외과) ;
- 박영주 (한림대학교 의과대학 치과학교실 구강악안면외과) ;
- 박희건 (한림대학교 의과대학 치과학교실 구강악안면외과) ;
- 박준우 (한림대학교 의과대학 치과학교실 구강악안면외과) ;
- 이건주 (한림대학교 의과대학 치과학교실 구강악안면외과) ;
- 이용찬 (한림대학교 의과대학 치과학교실 구강악안면외과) ;
- 조병욱 (한림대학교 의과대학 치과학교실 구강악안면외과)
- Published : 2001.10.30
Abstract
Purpose : Traditionally, the treatement of choice has been a bone grafting procedure to increase the length of bone in case of actual length discrepancy. But, bone grafting procedure has many disadvantages, for example, graft resorption, donor site morbidity, and so on. So, many trials have been performed to avert the use of autogenous bone graft via introducing new materials or methods. And, one of those trials has been realized by the development of a technique inducing bone lengthening by osteotomy (or corticotomy) and slow gradual distraction of the osteotomized segments. This new technique of bone lengthening dates back to the early 20th century. But, the majority of information concerning the biology of new bone formation during bone lengthening and technical details of the procedure were produced by extensive clinical and experimental studies performed by Ilizarov, a Russian surgeon. According to Ilizarov, with adequate blood supply, preservation of periosteum, rigid fixation of the osteotomized segments, and proper rate and rhythm of distraction, intramembranous bone rapidly develops within the distraction gap in the limb lengthening procedure. In the limb lengthening, many orthopedic surgeons try to observe the biologic and clinical principles recommended by Ilizarov. In the oral and maxillofacial region, however, not a few studies must be performed to apply this surgical technique in the clinical cases. Besides, the mechanism of bone formation in the distraction gap is not clear, yet. The purpose of this experiment was to scrutinize serially the histological changes in the elongated bone affected by osteodistraction of the mandibular body in an adult canine model. In addition, it was performed to confirm the presence of specific region(s) which was important in the bone formation in the gap through the observation of the expression pattern of osteocalcin and osteonectin with the immunohistochemical examination. Materials and Methods : The experimental and control specimens were obtained from seven adult male mongrel dogs weighing over 20kg. The distractors were custom-made linear extraoral devices and bicortical fixation screws were 2.3mm in diameter, 50mm in total length, 15mm in screw length. The distractors were devised to produce a linear gap of 0.75mm between two bony segments every