Journal of Pharmaceutical Investigation
- 제31권4호
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- Pages.209-216
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- 2001
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- 2093-5552(pISSN)
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- 2093-6214(eISSN)
In Vivo 레벨에서 1-아닐리노-8-나프탈렌 설포네이트(ANS)의 간내 이행 및 담즙배설 과정의 속도론적 해석
Kinetic Analysis of the Hepatic Uptake and Biliary Excretion of 1-Anilino-8-Naphthalene Sulfonate (ANS) in Vivo
- Bae, Woong-Tak (Research Lab., Dong-A Pharm. Co. Ltd.) ;
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Chung, Youn-Bok
(College of Pharmacy, Chungbuk National University) ;
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Han, Kun
(College of Pharmacy, Chungbuk National University)
- 발행 : 2001.12.20
초록
The purpose of the present study was to investigate the hepatic uptake and biliary excretion of l-anilino-8-naphthalene sulfonate (ANS) in vivo. The plasma concentration and liver concentration of ANS were determined after its i.v. bolus administration at a dose of