Journal of Pharmaceutical Investigation
- Volume 31 Issue 1
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- Pages.49-55
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- 2001
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- 2093-5552(pISSN)
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- 2093-6214(eISSN)
Bioequivalence of Neurocetil Tablet to Nicetile Tablet (Acetyl-L-Carnitine 500 mg)
니세틸 정(아세틸-엘-카르니틴 500 mg)에 대한 뉴로세틸 정의 생물학적 동등성
- Cho, Hea-Young (College of Pharmacy and Research Institute of Drug Development, Chonnam National University) ;
- Kim, Eun-A (College of Pharmacy and Research Institute of Drug Development, Chonnam National University) ;
- Jeong, Hyun-Cheol (College of Pharmacy and Research Institute of Drug Development, Chonnam National University) ;
- Shim, Young-Sun (College of Pharmacy and Research Institute of Drug Development, Chonnam National University) ;
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Lim, Dong-Koo
(College of Pharmacy and Research Institute of Drug Development, Chonnam National University) ;
- Oh, In-Joon (College of Pharmacy and Research Institute of Drug Development, Chonnam National University) ;
- Moon, Jai-Dong (Medical School, Chonnam National University) ;
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Lee, Yong-Bok
(College of Pharmacy and Research Institute of Drug Development, Chonnam National University)
- 조혜영 (전남대학교 약학대학/약품개발연구소) ;
- 김은아 (전남대학교 약학대학/약품개발연구소) ;
- 정현철 (전남대학교 약학대학/약품개발연구소) ;
- 심영순 (전남대학교 약학대학/약품개발연구소) ;
-
임동구
(전남대학교 약학대학/약품개발연구소) ;
- 오인준 (전남대학교 약학대학/약품개발연구소) ;
- 문재동 (전남대학교 의과대학) ;
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이용복
(전남대학교 약학대학/약품개발연구소)
- Published : 2001.03.20
Abstract
Acetyl-L-carnitine (ALC), an endogenous component of the L-carnitine family, is naturally occurring molecule synthesized from L-carnitine (LC) by carnitine acetyl transferase. ALC has been shown to improve the cognitive performance of patients suffering from dementia of the Alzheimer's type and proposed for treating Alzheimer's disease in pharmacological doses. The purpose of the present study was to evaluate the bioequivalence of two ALC tablets,