Journal of Pharmaceutical Investigation
- Volume 31 Issue 1
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- Pages.19-25
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- 2001
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- 2093-5552(pISSN)
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- 2093-6214(eISSN)
A Ternary Polymeric Matrix System for Controlled Drug Delivery of Highly Soluble Drug with High Drug Loading : Diltiazem Hydrochloride
염산 딜티아젬의 방출을 제어하기 위한 삼중 폴리머 매트릭스 시스템
- Kim, Hyun-Jo (Bukwang Pharmaceutical Ind. Co., Ltd.) ;
- Fassihi, Reza (Temple University)
- Published : 2001.03.20
Abstract
The purpose of this study was to use a ternary polymeric matrix system for high drug loading of a highly soluble drug for controlled release delivery. The controlled drug delivery of diltiazem HCl (solubility > 50% in water at
Keywords
- Ternary polymeric matrix;
- Diltiazem HCl;
- Controllrd release system;
- Swelling;
- Comparable release profile;
- Binding study