생약학회지 (Korean Journal of Pharmacognosy)
- 제32권3호통권126호
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- Pages.181-188
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- 2001
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
호장근의 쿠마린에 의한 RAW 264.7 세포주의 nitric oxide 생성 저해활성
Inhibition of Nitric Oxide Synthesis by Coumarins from Polygonum cuspidatum in LPS-Activated RAW 264.7 cells
- 노태철 (한국생명공학연구원 순환기연구실) ;
- 최희철 (한국생명공학연구원 순환기연구실) ;
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이승웅
(한국생명공학연구원 순환기연구실) ;
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김영호
(충남대학교 약학대학) ;
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노문철
(한국생명공학연구원 순환기연구실) ;
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김영국
(한국생명공학연구원 순환기연구실) ;
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이현선
(한국생명공학연구원 순환기연구실)
- Rho, Tae-Cheol (Cadiovascular Research Laboratory, Korea Research Institute of Bioscience and Biotechnology) ;
- Choi, Hee-Cheol (Cadiovascular Research Laboratory, Korea Research Institute of Bioscience and Biotechnology) ;
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Lee, Seung-Woong
(Cadiovascular Research Laboratory, Korea Research Institute of Bioscience and Biotechnology) ;
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Kim, Young-Ho
(College of Pharmacy, Chungnam National University) ;
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Rho, Mun-Chual
(Cadiovascular Research Laboratory, Korea Research Institute of Bioscience and Biotechnology) ;
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Kim, Young-Kook
(Cadiovascular Research Laboratory, Korea Research Institute of Bioscience and Biotechnology) ;
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Lee, Hyun-Sun
(Cadiovascular Research Laboratory, Korea Research Institute of Bioscience and Biotechnology)
- 발행 : 2001.09.30
초록
During the screening for inhibitors of nitric oxide production in LPS-activated macrophage, RAW 264.7 cells, two coumarins were isolated from chloroform extract of the root of Polygonum cuspidatum. They were identified as decursin (1) and decursinol angelate (2) on the basis of spectroscopic methods. The