Korean Journal of Pharmacognosy (생약학회지)
- Volume 32 Issue 2 Serial No. 125
- /
- Pages.121-127
- /
- 2001
- /
- 0253-3073(pISSN)
- /
- 2288-9299(eISSN)
Protective Effects of Bear Bile against Hepatotoxicity Induced by 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) in Mice
마우스에서 2,3,7,8-Tetrachlorodibenzo-p-dioxin(TCDD)에 의해 유발된 간독성에 대한 웅담의 방어효과
- Zhang, Hu-Song (College of Veterinary Medicine, Chungbuk National University) ;
- Nam, Sang-Yoon (College of Veterinary Medicine, Chungbuk National University) ;
- Kang, Jong-Koo (College of Veterinary Medicine, Chungbuk National University)
- Published : 2001.06.30
Abstract
The effect of bear bile on 2,3,7,8-tetrachlorodibenzo- p-dioxin (TCDD)-induced hepatotoxicity was investigated in 6-week-old C57BL/6 male mice. Bear bile (100 mg/kg or 500 mg/kg) was administered orally daily for 4 weeks, respectively. From the second week,
Keywords
- 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD);
- bear bile;
- lipid peroxidation;
- C57BL/6 mice;
- hepatoprotective effect