생약학회지 (Korean Journal of Pharmacognosy)
- 제32권2호통권125호
- /
- Pages.168-174
- /
- 2001
- /
- 0253-3073(pISSN)
- /
- 2288-9299(eISSN)
Quinone reductase 유도활성 측정에 의한 약용식물의 항암활성 검색
Induction of Quinone Reductase by Extracts of Traditional Medicinal Plants
- Jin, Hai-Hong (Department of Biotechnology, Graduate School, Handong University) ;
- Kim, Dong-Man (Yanbian University of Science and Technology, Department of Biochemical Engineering) ;
- Hyun, Chang-Kee (School of Bioscience and Food Technology, Handong University)
- 발행 : 2001.06.30
초록
Induction of phase II enzymes is a major mechanism of chemoprevention. The induction levels of quinone reductase (QR) activity in cultured murine hepatoma (Hepa 1c1c7) cells by 80%-methanol extracts of traditional medicinal plants were measured. Among the tested 81 plants, the extracts of Aralia continentalis, Magnolia obovata, and Viscum album were found to induce QR activities over 250%. The maximum induction levels obtained were 401.9%, 270.5%, and 301.8% by treatments of the extracts of A. continentalis