Natural Product Sciences
- Volume 7 Issue 3
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- Pages.90-93
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- 2001
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- 1226-3907(pISSN)
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- 2288-9027(eISSN)
The Effect of Opuntia ficus-indica var. saboten Fruit on Gastric Lesion and Ulcer in Rats
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Lee, Eun-Bang
(Natural Products Research Institute, Seoul National University)
;
- Hyun, Jin-Ee (Natural Products Research Institute, Seoul National University) ;
- Li, Da-Wei (Natural Products Research Institute, Seoul National University) ;
- Moon, Yung-In (Pukjeju Agricultural Development and Technology Extension Center)
- Published : 2001.09.01
Abstract
The effects of the dried fruit powder of Opuntia ficus-indica var. saboten (OF-f) were investigated on gastric lesion and ulcer models in rats. It showed significant inhibition in HCl ethanol and HCl aspirin induced gastric lesion at a dose of 600 mg/kg, p.o. OF-f also showed significant inhibition in indomethacin induced gastric lesion at the doses of 200 and 600 mg/kg, p.o. However, it did not affect aspirin and Shay ulcer in rats. It also did not affect the gastric juice secretion, acid output and pH. These data suggest that OF-f possesses pronounced inhibitory action on gastric lesion of rats.