The Korean Journal of Physiology and Pharmacology
- Volume 5 Issue 5
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- Pages.381-388
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- 2001
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- 1226-4512(pISSN)
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- 2093-3827(eISSN)
KR 31378, a Potent Antioxidant, Inhibits Apoptotic Death of A7r5 Cells
- Kim, Ki-Young (Division of Biological Sciences, College of Natural Sciences, Pusan National University) ;
- Kim, Byeong-Gee (Division of Biological Sciences, College of Natural Sciences, Pusan National University) ;
- Kim, Sun-Ok (Dongbu Hannong Chemical Co.) ;
- Yoo, Sung-Eun (Research Institute of Chemical Technology) ;
- Hong, Ki-Whan (Department of Pharmacology, Research Institute of Genetic Engineering, Pusan National University)
- Published : 2001.10.21
Abstract
This work describes the pharmacological inhibition by KR 31378 and its acetyl metabolite, KR 31612, of the apoptotic cell death induced by
Keywords
- KR 31378;
- ${\alpha}-Tocopherol$;
- Oxidative stress;
- Apoptosis;
- Reactive oxygen species;
- Bcl-2;
- Bax;
- Cytochrome C