Korean Journal of Biological Psychiatry (생물정신의학)

The Korean Society of Biological Psychiatry (대한생물정신의학회)
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Comparison of Global Field Power Measurement and Conventional Method in Multi-channel Auditory Event Related Potential P300 Determination

다채널 청각 사건관련전위 P300 결정에서 전부위장력측정법과 전통적방법의 비교

  • Jeon, Yang-Whan (Department of Neuropsychiatry, Our Lady of Mercy Hospital, The Catholic University of Korea) ;
  • Han, Sang-Ick (Department of Neuropsychiatry, Our Lady of Mercy Hospital, The Catholic University of Korea)
  • 전양환 (가톨릭대학교 의과대학 성모자애병원 신경정신과) ;
  • 한상익 (가톨릭대학교 의과대학 성모자애병원 신경정신과)
  • Published : 2000.12.31
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Abstract

Objective : The present study was designed to compare Global Field Power Measurement and conventional method in P300 determination. Method : The subjects were composed of patients(N=20) with schizophrenia by DSM-IV and normal controls(N=20). The auditory event related potential P300 was measured by "oddball paradigm". P300 components were determined by Global Field Power Measurement and conventional method at 5 electrodes(Fz, Cz, Pz, $T_3$, $T_4$). Results : P300 amplitudes of patients were smaller than those of controls across all electrodes and in both methods, but there was no differential power in P300 determination between two methods. Asymmetry of auditory event-related potential P300 was not shown between patients with schizophrenia and normal controls. Conclusion : It is implicated that it depends on clinical situations and research purposes what method of P300 determination will be more appropriate for patients with schizophernia.

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