Clinical and Experimental Reproductive Medicine
- Volume 27 Issue 2
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- Pages.117-131
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- 2000
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- 2233-8233(pISSN)
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- 2233-8241(eISSN)
Expression Pattern of Progesterone Receptor, Integrin, Cyclooxygenase (COX) in Human Endometrium of Patients with Endometriosis
자궁내막증 환자의 자궁내막내 성호르몬 수용체, Integrins, Cyclooxygenase의 발현과 변이 양상
- Kim, Mi-Ran (Department of Obstetrics and Gynecology, Ajou University School of Medicine) ;
- Park, Dong-Wook (Department of Obstetrics and Gynecology, Ajou University School of Medicine) ;
- Kwon, Hyuek-Chan (Department of Obstetrics and Gynecology, Ajou University School of Medicine, Department of Molecular Science and Technology) ;
- Hwang, Kyoung-Joo (Department of Obstetrics and Gynecology, Ajou University School of Medicine) ;
- Joo, Hee-Jae (Department of Pathology, Ajou University School of Medicine) ;
- Cho, Dong-Jae (Department of Obstetrics and Gynecology, Yonsei University College of Medicine) ;
- Kim, Sei-Kwaug (Department of Obstetrics and Gynecology, Yonsei University College of Medicine) ;
- Oh, Kie-Suk (Department of Obstetrics and Gynecology, Ajou University School of Medicine)
- 김미란 (아주대학교 의과대학 산부인과학교실) ;
- 박동욱 (아주대학교 의과대학 산부인과학교실) ;
- 권혁찬 (아주대학교 의과대학 산부인과학교실, 아주대학교 대학원 분자과학기술과) ;
- 황경주 (아주대학교 의과대학 산부인과학교실) ;
- 주희재 (아주대학교 의과대학 해부병리학교실) ;
- 조동제 (연세대학교 의과대학 산부인과학교실) ;
- 김세광 (연세대학교 의과대학 산부인과학교실) ;
- 오기석 (아주대학교 의과대학 산부인과학교실)
- Published : 2000.06.30
Abstract
Objectives: To develop a new immunohistochemical marker system for supplementation of the Noyes histological classification of the endometrium in women of child bearing age with regular menstrual cycles, and to employ this system to evaluate pathologic factors involved in endometriosis, and thus to ascertain if it is useful in diagnosis. Materials and Methods: Endometrial biopsies were sampled from the posterior fundus of 41 (24 proliferative phases, 17 secretory phases) women with regular menstrual cycles (28-32 days), and each sample was immunohistochemically stained according to Noyes et al (1975) for determination of expression for estrogen receptor (ER), progesterone receptor (PR), integrin