Journal of Korean Neurosurgical Society
- Volume 29 Issue 12
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- Pages.1584-1591
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- 2000
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- 2005-3711(pISSN)
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- 1598-7876(eISSN)
Immunohistochemical Study for the Angiogenesis Factors and Vascular Wall Matrix Proteins in Intracranial Aneurysms
뇌동맥류에서 혈관형성 인자와 혈관벽 기질 단백에 대한 면역조직화학적 연구
- Kim, Jae Hong (Department of Neurosurgery, Keimyung University School of Medicine) ;
- Yim, Man Bin (Department of Neurosurgery, Keimyung University School of Medicine) ;
- Lee, Chang Young (Department of Neurosurgery, Keimyung University School of Medicine) ;
- Kim, Sang Pyo (Department of Pathology, Keimyung University School of Medicine)
- 김재홍 (계명대학교 의과대학 신경외과학교실) ;
- 임만빈 (계명대학교 의과대학 신경외과학교실) ;
- 이창영 (계명대학교 의과대학 신경외과학교실) ;
- 김상표 (계명대학교 의과대학 병리학교실)
- Received : 2000.02.07
- Accepted : 2000.09.25
- Published : 2000.12.28
Abstract
Objective : Until now, it has been little known about the biological mechanisms associated with the genesis, growth, and rupture of intracranial aneurysm. This study was performed to investigate and understand a part of these mechanisms. Materials and Methods : Immunohistochemical stains for angiogenesis growth factors(basic fibroblast growth factor (bFGF) and vascular endothelial growth factor(VEGF)) and selected vascular wall matrix proteins(alpha smooth muscle actin(
Keywords
- Aneurysm;
- Basic fibroblast growth factor;
- Vascular endothelial growth factor;
- Alpha smooth muscle actin;
- Collagen type IV