Journal of Korean Neurosurgical Society
- Volume 29 Issue 2
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- Pages.167-179
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- 2000
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- 2005-3711(pISSN)
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- 1598-7876(eISSN)
The Time and Effect of Hypothermia in Early Stage of the Reversible Cerebral Focal Ischemic Model of Rat
백서의 가역성 뇌허혈 모형에서 저체온의 효과와 적용시기
- Choi, Byung-Yon (Department of Neurosurgery, College of Medicine, Yeungnam University) ;
- Jung, Byung-Woo (Department of Neurosurgery, College of Medicine, Yeungnam University) ;
- Song, Kwang-Chul (Department of Neurosurgery, College of Medicine, Yeungnam University) ;
- Park, Jin-Han (Department of Neurosurgery, College of Medicine, Yeungnam University) ;
- Kim, Seong-Ho (Department of Neurosurgery, College of Medicine, Yeungnam University) ;
- Bae, Jang-Ho (Department of Neurosurgery, College of Medicine, Yeungnam University) ;
- Kim, Oh-Lyong (Department of Neurosurgery, College of Medicine, Yeungnam University) ;
- Cho, Soo-Ho (Department of Neurosurgery, College of Medicine, Yeungnam University) ;
- Kim, Seung-Lae (Department of Neurosurgery, College of Medicine, Kyungpook National University)
- 최병연 (영남대학교 의과대학 신경외과학교실) ;
- 정병우 (영남대학교 의과대학 신경외과학교실) ;
- 송광철 (영남대학교 의과대학 신경외과학교실) ;
- 박진한 (영남대학교 의과대학 신경외과학교실) ;
- 김성호 (영남대학교 의과대학 신경외과학교실) ;
- 배장호 (영남대학교 의과대학 신경외과학교실) ;
- 김오룡 (영남대학교 의과대학 신경외과학교실) ;
- 조수호 (영남대학교 의과대학 신경외과학교실) ;
- 김승래 (경북대학교 의과대학 신경외과학교실)
- Received : 1999.06.21
- Accepted : 1999.07.28
- Published : 2000.02.28
Abstract
Objective : We studied to clarify the effective time zone of mild hypothermic neural protection during ischemia and/or reperfusion after middle cerebral artery occlusion. Methods : In a reversible cerebral infarct model which maintained reperfusion of blood flow after middle cerebral artery occlusion for two hours, the size of cerebral infarction, cerebral edema and the extent of neurological deficit were observed and analyzed for comparison between the control and the experimental groups under hypothermia(