Journal of Korean Neurosurgical Society
- Volume 29 Issue 1
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- Pages.5-14
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- 2000
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- 2005-3711(pISSN)
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- 1598-7876(eISSN)
Change of Somatosensory Evoked Field Potential according to the Severity of Hydrocephalus in Kaolin-induced Hydrocephalus of Rats
수두증 흰쥐 모델에서 수두증 정도에 따른 체성 감각 유발 장전위의 변화
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Kim, Dong-Seok
(Department of Neurosurgery, Brain Research Institute & Medical Research Center, Yonsei University College of Medicine) ;
- Lee, Kwang-Soo (Department of Neurosurgery, Brain Research Institute & Medical Research Center, Yonsei University College of Medicine) ;
- Park, Yong-Goo (Department of Neurosurgery, Brain Research Institute & Medical Research Center, Yonsei University College of Medicine) ;
- Kim, Se-Hyuk (Department of Neurosurgery, Brain Research Institute & Medical Research Center, Yonsei University College of Medicine) ;
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Choi, Joong-Uhn
(Department of Neurosurgery, Brain Research Institute & Medical Research Center, Yonsei University College of Medicine) ;
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Lee, Bae-Hwan
(Department of Neurosurgery, Brain Research Institute & Medical Research Center, Yonsei University College of Medicine) ;
- Ryou, Jae-Wook (Department of Neurosurgery, Brain Research Institute & Medical Research Center, Yonsei University College of Medicine) ;
- Zhao, Chun-Zhi (Department of Neurosurgery, YanBian University, Medical College Hospital)
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김동석
(연세대학교 의과대학 뇌연구소, 임상연구동 신경외과학교실) ;
- 이광수 (연세대학교 의과대학 뇌연구소, 임상연구동 신경외과학교실) ;
- 박용구 (연세대학교 의과대학 뇌연구소, 임상연구동 신경외과학교실) ;
- 김세혁 (연세대학교 의과대학 뇌연구소, 임상연구동 신경외과학교실) ;
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최중언
(연세대학교 의과대학 뇌연구소, 임상연구동 신경외과학교실) ;
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이배환
(연세대학교 의과대학 뇌연구소, 임상연구동 신경외과학교실) ;
- 류재욱 (연세대학교 의과대학 뇌연구소, 임상연구동 신경외과학교실) ;
- Received : 1999.04.30
- Accepted : 1999.09.14
- Published : 2000.01.28
Abstract
Objective : Somatosensory evoked potential(SSEP) has been known to be a good method for evaluating brain stem function, but it is not sufficient to check the fine changes of cortical functions. A fine change of cortical function can be expressed with somatosensory evoked cortical field potential(SSEFP) rather than general SSEP. To confirm the usefulness of SSEFP for evaluating the cortical function, the authors simultaneously measured SSEFP and the intracranial pressure-volume index(PVI) in kaolin-induced hydrocephalic rats. Method : Hydrocephalus was induced with injection of 0.1ml kaolin-suspended solution into the cisterna magna in 60 Sprague-Dawley rats. The authors measured PVI and SSEFP 1 week after injection of kaolin-suspended solution. To evaluate the severity of induced hydrocephalus, we measured the transverse diameter of the lateral ventricle on the coronal slice of the rat brain 0.40mm posterior to the bregma. Result : The typical wave form of SSEFP in control rats showed a negative-positive complex wave at early latency. In SSEFP of normal rats, N0 is 10.0 msec, N1 15.3 msec, P1 31.2 msec and N1-P1 amplitude
Keywords
- Kaolin-induced hydrocephalus;
- Pressure-volume index;
- Somatosensory evoked potential;
- Somatosensory evoked cortical field potential