Restorative Dentistry and Endodontics
- 제25권1호
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- Pages.63-70
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- 2000
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- 2234-7658(pISSN)
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- 2234-7666(eISSN)
역충전재의 생체적합성에 관한 연구
BIOCOMPATIBILITY OF RETROGRADE FILLING MATERIALS
- 임미경 (원광대학교 치과대학 치과보존학교실)
- Im, Mi-Kyung (Department of Conservative Dentistry, College of Dentistry, Wonkwang university)
- 발행 : 2000.03.05
초록
The properties of ideal retrograde filling materials include the ability to seal the root canal system in three dimensions and well tolerated by periradicular tissues. Biocompatibility testing has been done mainly with cytotoxicity tests using cell culture. Little attention has been paid to the potential adverse influence on the inflammatory and immune reaction in the periapical tissue. The purpose of this study was to investigate the effects of retrograde filling materials on human mononuclear cells in vitro. Freshly mixed and set specimens from six materials (Z100, Tetric Ceram, Fuji II, Fuji II LC, F2000, Compoglass Flow, and ZOE) were eluated with cell culture medium for 24 hours. Cytotoxic effects of these extracts were evaluated by determining cell viability and enzyme activity using MTT and lactate dehydrogenase (LD). The production of inflammatoy bone resorptive cytokine, TNF-