혜화의학회지 (Journal of Haehwa Medicine)

  • 제9권1호
  • /
  • Pages.135-142
  • /
  • 2000
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  • 2586-3002(pISSN)
  • /
  • 2586-3347(eISSN)
대전대학교 한의학연구소 (Research Institute of Korean Medicine)
권호 표지

홍삼복합방(紅蔘複合方)의 보간작용(補肝作用)에 대(對)한 실험적(實驗的) 연구(硏究)(1)

Study on protective effect on hepatic damage by alcohol and CCl4 by Korea red ginseng-mixed formula

  • 강창희 (대전대학교 한의과대학 병리학교실) ;
  • 김성훈 (경희대학교 동서의학대학원 한방종양학교실) ;
  • 최봉균 (푸른 한의원) ;
  • 김동희 (대전대학교 한의과대학 병리학교실)
  • 발행 : 2000.08.25
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초록

For the evaluation of protective effect on hepatic damage by Korean red ginseng mixed formula, we used GR(Korean red ginseng), GRF-A(Korean red ginseng-mixed formula) as a materials. The study was performed on protective effect against hepatic damage induced by $CCl_4$. In vitro assay with 1.1 mM galactosamine, protection(%) was 44%(GR), 58%(GRF-A) at 50ug/ml, while maxium protection(%) was 5%(GR) and 24% (GRF-A) against acute hepatotoxicity by $CCl_4$. GRF-A significantly protected ethanol induced-liver damage by lowering ALT and ALP and fatty degenertion in liver tissue.

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