Fisheries and Aquatic Sciences

한국수산과학회 (The Korean Society of Fisheries and Aquatic Science)
권호 표지

Relationship between Viral Propagation and Apoptosis after Marine Birnavirus (MABV) Infection

  • Kim Yeong Jin (Department of Fish Pathology, Yosu National University) ;
  • Choi Won Chul (Department of Biology, Pusan National University) ;
  • Kim Hyeung Rak (Department of Food Science & Biotechnology, Pukyung National University) ;
  • Jung Sung Ju (Department of Fish Pathology, Yosu National University) ;
  • Jung Tae Sung (Department of Microbiology, College of Medicine, Gyeongsang National University) ;
  • Kim Jae Ho (Graduate School of Biotechnology, Korea University) ;
  • Yeo In Kyu (Department of Marine Biotechnology, Cheju National University) ;
  • Oh Myung Joo (Department of Fish Pathology, Yosu National University)
  • 발행 : 2000.06.01
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초록

This study was performed to confirm the relationship between viral propagation and apoptosis by the infection of marine birnavirus strain (MABV NF-4) on chinook salmon embryo (CHSE-214) cells. After 6 hr viral infection, MABV was detected by PCR method. Also, as a result of DNA assay on the cells, MABV infection resulted in a typical feature of apoptosis, DNA fragmentation. The results suggest that MABV replicated to high concentrations during the early stage of infection induces apoptosis.

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