Journal of Preventive Medicine and Public Health
- 제33권2호
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- Pages.226-230
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- 2000
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- 1975-8375(pISSN)
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- 2233-4521(eISSN)
보건예방사업을 위한 B형간염 표면항체 검사방법 비교
Comparison of Methods for the Detection of Anti-HBs for Hepatitis B Vaccination Program in Korea
- 이정녀 (인제대학교 부산백병원 임상병리학과) ;
- 엄상화 (인제대학교 의과대학 예방의학교실) ;
- 이종태 (인제대학교 의과대학 예방의학교실) ;
- 전진호 (인제대학교 의과대학 예방의학교실) ;
- 손혜숙 (인제대학교 의과대학 예방의학교실)
- Lee, Jeong-Nyeo (Department of Clinical Pathology, Pusan Paik Hosipital, Inje University) ;
- Urm, Sang-Hwa (Department of Preventive Medicine, Inje University) ;
- Lee, Jong-Tae (Department of Preventive Medicine, Inje University) ;
- Chun, Jin-Ho (Department of Preventive Medicine, Inje University) ;
- Sohn, Hae-Sook (Department of Preventive Medicine, Inje University)
- 발행 : 2000.06.01
초록
Objectives : The purpose of this study was to suggest a proper method for the detection of heaptitis B surface antibody(anti-HBs) in a screening program for hepatitis B vaccination. Methods : Sensivitity, specificity and predictive values were compared between Immunochromatographic assay (ICA) and passive hemagglutination(PHA) in 978 subjects(565 males, 413 females, 19-78 years ranging in age, mean 46.5 years old). EIA was used as a standard method for the detection of HBsAb. Results : Sensitivity in the detection of anti-HBs of PHA and ICA was 88.7%, and 94.9%, specificity was 94.3% and 96.6%, negative predictive value was 96.5%, and 98.0%, and positive predictive value was 82.3%, and 91.3%,, respectively. False negative rate(11.3%) of PHA was higher than that(5.1%) of ICA. The higher the titer of anti-HBs in EIA was, the lower the false negative rate was. There was no false negative result in the cases with