Journal of Preventive Medicine and Public Health
- Volume 33 Issue 2
- /
- Pages.226-230
- /
- 2000
- /
- 1975-8375(pISSN)
- /
- 2233-4521(eISSN)
Comparison of Methods for the Detection of Anti-HBs for Hepatitis B Vaccination Program in Korea
보건예방사업을 위한 B형간염 표면항체 검사방법 비교
- Lee, Jeong-Nyeo (Department of Clinical Pathology, Pusan Paik Hosipital, Inje University) ;
- Urm, Sang-Hwa (Department of Preventive Medicine, Inje University) ;
-
Lee, Jong-Tae
(Department of Preventive Medicine, Inje University) ;
-
Chun, Jin-Ho
(Department of Preventive Medicine, Inje University) ;
-
Sohn, Hae-Sook
(Department of Preventive Medicine, Inje University)
- 이정녀 (인제대학교 부산백병원 임상병리학과) ;
- 엄상화 (인제대학교 의과대학 예방의학교실) ;
-
이종태
(인제대학교 의과대학 예방의학교실) ;
-
전진호
(인제대학교 의과대학 예방의학교실) ;
-
손혜숙
(인제대학교 의과대학 예방의학교실)
- Published : 2000.06.01
Abstract
Objectives : The purpose of this study was to suggest a proper method for the detection of heaptitis B surface antibody(anti-HBs) in a screening program for hepatitis B vaccination. Methods : Sensivitity, specificity and predictive values were compared between Immunochromatographic assay (ICA) and passive hemagglutination(PHA) in 978 subjects(565 males, 413 females, 19-78 years ranging in age, mean 46.5 years old). EIA was used as a standard method for the detection of HBsAb. Results : Sensitivity in the detection of anti-HBs of PHA and ICA was 88.7%, and 94.9%, specificity was 94.3% and 96.6%, negative predictive value was 96.5%, and 98.0%, and positive predictive value was 82.3%, and 91.3%,, respectively. False negative rate(11.3%) of PHA was higher than that(5.1%) of ICA. The higher the titer of anti-HBs in EIA was, the lower the false negative rate was. There was no false negative result in the cases with