Korean Journal of Veterinary Research (대한수의학회지)
- Volume 40 Issue 4
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- Pages.691-699
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- 2000
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- 2466-1384(pISSN)
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- 2466-1392(eISSN)
The inhibitory action of nitric oxide donor on the slow wave and spontaneous contraction in the guinea pig antral circular muscle
기니피그 유문부 윤상근의 서파 몇 자발적 수축에 대한 nitric oxide donor의 억제적 작용
- Kim, Tea-wan (Department of Physiology, College of Veterinary Medicine, Seoul National University) ;
- La, Jun-ho (Department of Physiology, College of Veterinary Medicine, Seoul National University) ;
- Yang, Il-suk (Department of Physiology, College of Veterinary Medicine, Seoul National University)
- Accepted : 2000.11.23
- Published : 2000.12.20
Abstract
We investigated the effects of nitric oxide (NO) donors, S-nitroso-L-cysteine (Cys-NO) and 3-morpholinosydnonimine hydrochloride (SIN-1), on the contractile and electrical activity of the circular muscle of guinea pig gastric antrum by using intracellular microelectrode technique. The gastric antral circular muscle showed spontaneous phasic contraction and slow wave of membrane potential. Cys-NO (