한국응용과학기술학회지 (Journal of the Korean Applied Science and Technology)
- 제17권4호
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- Pages.267-272
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- 2000
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- 1225-9098(pISSN)
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- 2288-1069(eISSN)
DOI QR Code
Sulfa제의 Dual Action에 의한 지속성과 항균성
Antibiotics and Durability by Action of Sulfa Agents
- 공승대 (명지대학교 세라믹화학공학부) ;
- 황성규 (명지대학교 세라믹화학공학부) ;
- 윤철훈 (명지대학교 세라믹화학공학부) ;
- 김진영 (건국대학교 화학생물공학부 신소재공학) ;
- 이한섭 (용인대학교 환경보건학과)
- Kong, Seung-Dae (Div. of Ceramic & Chemical Engineering, Myong Ji Univ.) ;
- Hwang, Sung-Kwy (Div. of Ceramic & Chemical Engineering, Myong Ji Univ.) ;
- Yoon, Cheol-Hun (Div. of Ceramic & Chemical Engineering, Myong Ji Univ.) ;
- Kim, Jin-Yeong (Dept. of Materials chemistry & Engineering, Kon Kuk Univ.) ;
- Lee, Han-Seob (Dept. of Environmental Health, Yong In Univ.)
- 발행 : 2000.12.31
초록
Dual-actions are the most recently used delivery system in drug study. Dual-action agents are unique chemical entities comprised of two different type of antibacterial compounds covalently linked together in a single molecule in such a way that both components are able to exert their bactericidal properties. Crosslinked sulfadiazine-sulfanilamide such as antibiotics is synthesized by synthetic handle with glutaraldehyde. As a result, New synthetic antibacterial agent exhibited the broad antibacterial activities against gram(+) and gram(-) of 4 strains and a long durability supposing that the stomach and blood.
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