Journal of Applied Biological Chemistry
- Volume 43 Issue 4
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- Pages.185-191
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- 2000
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- 1976-0442(pISSN)
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- 2234-7941(eISSN)
Insecticide Targets: Learning to Keep Up with Resistance and Changing Concepts of Safety
- Casida, John E. (Environmental Chemistry and Toxicology Laboratory, Department of Environmental Science, Policy and Management, University of California) ;
- Quistad, Gary B. (Environmental Chemistry and Toxicology Laboratory, Department of Environmental Science, Policy and Management, University of California)
- Received : 2000.10.25
- Published : 2000.12.31
Abstract
Pest insect control is dependent on about 200 insecticides that work by relatively few mechanisms. The targets they disrupt are mostly involved in the nervous system, respiratory chain, growth and development, or the gut. The major nerve targets are: acetylcholinesterase for the organophosphates and methylcarbamates; the nicotinic acetylcholine receptor for the neonicotinoids; the
Keywords
- esterase and amidase inhibitors;
- nicotinic acetylcholine receptor;
- $\gamma$-aminobutyric acid receptor;
- respiratory inhibitors