Pediatric Infection and Vaccine

The Korean Society of Pediatric Infectious Diseases (대한소아감염학회)
권호 표지

A Case of Rifampin-induced Thrombocytopenia in Pulmonary Tuberculosis

Rifampin으로 폐결핵 치료 중 발생한 혈소판 감소증 1례

  • Park, Seok Won (Department of Pediatrics, Wonju College of Medicine, Yonsei University) ;
  • Cho, Hee Suk (Department of Pediatrics, Wonju College of Medicine, Yonsei University) ;
  • Kim, Hwang Min (Department of Pediatrics, Wonju College of Medicine, Yonsei University) ;
  • Lim, Baek Keun (Department of Pediatrics, Wonju College of Medicine, Yonsei University) ;
  • Kim, Jong Soo (Department of Pediatrics, Wonju College of Medicine, Yonsei University)
  • 박석원 (연세대학교 원주의과대학 소아과학교실) ;
  • 조희숙 (연세대학교 원주의과대학 소아과학교실) ;
  • 김황민 (연세대학교 원주의과대학 소아과학교실) ;
  • 임백근 (연세대학교 원주의과대학 소아과학교실) ;
  • 김종수 (연세대학교 원주의과대학 소아과학교실)
  • Published : 2000.11.30
Download PDF
⟨ Previous Next ⟩

Abstract

Rifampin is a bactericidal antibiotic used primarily in the treatment of tuberculosis. The adverse effects of rifampin, though few, include dermatologic, gastrointestinal, and hepatic manifestations. Occasionally it produces a flu-like syndrome, interstitial nephritis, hemolytic anemia, and thrombocytopenia. These manifestations usually appear in patients who take the drug intermittently. We experienced a 13 year-old girl who developed thrombocytopenia during rifampin administration of daily dosage, therefore we report a brief review with the related literatures.

저자들은 흉막삼출액을 동반한 폐결핵으로 입원한 13세 여아가 isoniazid 및 rifampin으로 치료 중 혈소판 감소증을 보였으며, 혈소판이 정상으로 회복된 후 리팜핀의 재투여로 발생한 혈소판 감소증 1례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

Keywords