N-{2,4-Dichloro-5-(3-pyrazolyl)phenyl}imides 유도체의 합성 및 제초활성

Synthesis and Herbicidal Activity of N-{2,4-dichloro-5-(3-pyrazolyl)Phenyl} imides

제초제 후보물질로서 N-{2,4-dichloro-5-(N-methylpyrazol-3-yl)phenyl}imides 7과 N-{2,4-dichloro-5-(N-methy-lpyrazol-5-yl))Phenyl}imides 8의 유도체들을 합성하여 제초활성을 온실조건에서 조사하였다. 처리량 1 kg/ha에서 pyrazole moiety에 carboxylate나 carboxamide 치환기가 있는 화합물들 (7c-7l) 제초활성을 나타내지 않았으나, pyrazole moiety에 trifluoromethyl기가 있는 화합물들은 처리량 63-250 g/ha에서 논피, 물달개비, 너도방동산이등의 잡초들에 대해 제초활성을 보였고 벼에 대해서는 안전한 결과를 보였다.

A series of N-{2,4-dichloro-5-(3-pyrazolyl)Phenyl}imides 7 and 8 was prepared and evaluated their herbicidal activities. Those compounds in which either carboxylate or carboxamide moiety is on pyrazole moiety 7c-71 showed no herbicidal activity whereas, the compounds in which trifluoromethyl group is substituted in pyrazolyl moiety showed moderate herbicidal activities against barnyardgrass, monochria and flat-sedge under paddy conditions with good rice tolerance at rate 63-250 g/ha.