Macromolecular Research

The Polymer Society of Korea (한국고분자학회)
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Advances in Biodegradable Polymers for Drug Delivery Systems

  • Yong Kiel sung (Department of Chemistry, Dongguk University) ;
  • Kim, Sung-Wan (Center for Controlled Chemical Delivery, Department of Pharmaceutics and Pharmaceutical Chemistry, University of Utah)
  • Published : 2000.10.01
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Abstract

The recent development of biodegradable polymers for drug delivery system (DDS) has been investigated. The biodegradable polymers for DDS are mainly discussed in two categories: one category is natural biodegradable polymers such as polysaccharides, modified celluloses, poly(${\alpha}$-amino acid)s, modified proteins, and microbial biodegradable polymers; the other is synthetic biodegradable polymers such as poly(ester)s, poly(ortho ester)s, poly(phosphazene)s, poly(anhydride)s, poly(alkyl cyanoacrylate)s, and multiblock copolymers. The bioconjugate polymeric drug delivery systems have been also proposed for the design of biocompatible polymeric controlled drug delivery.

Keywords

References

  1. Nineth International Symposium on Recent Advances in Drug Delivery Systems, CCCD S. W. Kim;J. Kopecek;J. M. Anderson(eds)
  2. Chem. Rev. v.99 K. Uhrich;S. Cannizzaro;R. Langer;K. Shakesheff
  3. Handbook of Biodegradable Polymers A. J. Domb;J. Kost;D. M. Wisteman(Eds.)
  4. Biodegradable Polymers as Drug Delivery Systems M. Chain;R. Langer(Eds.)
  5. Drug Delivery Systems R. L. Juliano
  6. Polymeric Drug Delivery Systems-Drug Design v.5 S. W. Kim;R. V. Peterson;J. Feijen;J. Ariens(Ed.)
  7. Nature v.388 B. Jeong;Y. H. Bae;D. S. Lee;S. W. Kim
  8. Science v.249 R. Langer
  9. Biodegradable Hydrogels for Drug Delivery K. Park;W. S. W. Shalaby;H. Park
  10. ACS Symposium Series v.627 Hydrogels and Biodegradable Polymers for Bioapplications R. M. Ottenbrite;S. J. Huang;K. Park(Eds.)
  11. Polymer v.15 Y. K. Sung;I. K. Kang;D. R. Kwon
  12. Polymer v.15 Y. K. Sung;J. Y. Kim;Y. M. Lee;Y. K. Kim;C. S. Cho
  13. J. Control Rel. v.49 Y. K. Sung;J. H. Ha;S. H. Kim;S. Y. Han;C. S. Cho
  14. J. Biomed. Materials Res. v.15 H. R. Dickinson;A. Hiltner;D. F. Gibbons;J. M. Anderson
  15. J. Biomed. Materials Res. v.15 H. R. Dickinson;A. Hiltner
  16. J. Control. Rel v.28 H. Okada;M. Yamamoto;T. Heya;Y. Inoue;K. Kamei;Y. Ogawa;H. Toguchi
  17. J. Control. Rel. v.12 L. M. Sanders;G. I. McRac;K. M. Vitale;B. A. Kell
  18. Lancet v.345 H. Brem;S. Piantadosi;P. C. Burger;M. Walker;R. Selker;N. A. Black;M. Sisti;S. Brem;G. Mohr
  19. Drug Delivery to the Brain, in Polymeric Site Specific Pharmacotheraphy H. Brem;K. A. Walter;R. J. Tamargo;A. Olivi;R. Langer;A. Domb(Ed.)
  20. J. Control Rel. M. H. Seo;C. S. Kim;D. W. Kim;Y. H. Shim;S. W. Kim;J. H. Oh
  21. Molecular Therapy v.2 no.2 A. Maheshwari;R. I. Mahato;J. McGregor;S. Han;W. E. Samlowski;J. Park;S. W. Kim
  22. Natural and Modified Polysaccharides, in Handbook of Biodegradable Polymers J. Kost;R. Goldbalt;A. J. Domb(ed.);J. Kost(ed.);D. M. Wiseman(ed.)
  23. Chemical Modification of Proteins and Polysaccharides and Its Effect on Enzyme-Catalyzed Degradation, in Biomedical Polymers W. S. W. Shalby;K. Park;W.S. W. Shalby(ed.)
  24. J. Pharm. Sci. v.81 G. Vandenbossche;R. Leffebvre;G. De Wilde;J. P. Rernon
  25. J. Pharm. Sci. v.76 T. Laakso;I. Sjoholm
  26. J. Pharm. Sci. v.75 T. Laakso;P. Artursson;I. Sjoolm
  27. J. Pharm. Sci. v.80 P. Stjarnkvist;L. Degling;I. Sjoholm
  28. J. Pharm. Sci. v.78 P. Stjarnkvist;T. Laakso;I. Sjoholm
  29. Clin. Pharmacokinet. v.31 C. J. Johansson
  30. J. Pharmacol. Exp. Ther. v.231 P. Artursson;P. Edman;I. Sjoholm
  31. Biomaterials v.11 J. Kost;S. Shefer
  32. Biomaterials v.12 B. Crepon;J. Jozefonvicz;V. Chytry;B. Rihova;J. Kopecek
  33. J. Biomater. Sci. Polym. Ed. v.1 no.4 V. Subr;R. Duncan;J. Kopecek
  34. Pharm. Res. v.6 E. Harbae;C. Larsen;M. Johansen;H. P. Olesen
  35. J. Pharm. Sci. v.69 P. Edman;B. Ekman;I. Sjoholm
  36. Biomaterials v.3 no.2 S. H. Pangburn;P. V. Trescony;J. Heller
  37. Biotechnol. Prog. v.10 K. Itoyama;S. Tokura;T. Hayashi
  38. J. Kor. Ind. Eng. Chem. v.4 Y. K. Sung;S. J. Kim;Y. M. Lee;I. K. Kang;Y. H. Park
  39. Biomaterials v.10 S. Hirano;H. Tsuchida;N. Nagao
  40. J. Pharm. Pharmacol. v.39 C. Bindschaedler;R. Gurney;E. Doelker
  41. Handbook of Biodegradable Polymers Oxidized Cellulose R. L. Stilwell;M. G. Marks;L. Saferstein;D. M. Wiseman;A. J. Domb(Ed.);J. Kost(Ed.);D. M. Wiseman(Ed.)
  42. Surg. v.91 K. S. Scher;J. A. Coil
  43. J. Surg. Res. v.23 P. Dineen
  44. Surg. Gyneco. Obstet. v.142 P. Dineen
  45. Prog. Clin. Biol. Res. v.381 R. L. Reid;K. Lie;J. E. Spence;T. Tulandi;A. Yuzpe
  46. J. Surg. Res. v.53 D. M. Wiseman;L. Kamp;C. B. Linsky;R. F. Jochen;R. H. Pang;P. M. Scholz
  47. J. Pharm. Pharmacol. v.39 C. Bindschaedler;R. Gurny;E. Doelker
  48. J. Biochem. Biophys. Methods v.14 E. R. Tovey;S. A. Ford;B. A. Baldo
  49. Int. J. Pharm. v.40 J. L. Ford;M. H. Rubinstein;F. McCaul;J. E. Hogan;P. Edgar
  50. Protein Chem. v.13 E. Katchalsky;M. Sela
  51. Polymer Preprints v.20 J. M. Anderson;S. M. Fang;J. Feijen;D. Gregonis;S. W. Kim
  52. Pharm. Res. v.4 A. Negishi;D. B. Bennett;S. Y. Jeong;W. van Heeswijk;J. Feijen;S. W Kim
  53. J. Control. Rel. v.22 D. B. Bennett;X. Li;N. W. Adams;C. J. T. Hoes;J. Feijen;S. W. Kim
  54. J. Drug. Target. v.8 P. Lemieux;S. V. Vinogradov;C. L. Gebhart;N. Guerin;G. Paradis;H. K. Nguyen;B. Ochietti;Y. G. Suzdaltseva;E. V. Bartakova;T. K. bronich;Y. St-Pierre;V. Y. Alakhov;A. V. Kabanov
  55. Int. J. Pharm. v.200 A. Charlier;B. Leclerc;G. Couarraze
  56. J. Med. Chem. v.43 A. Bentolila;I. Vlodavsky;R. Ishai-Michaeli;O. Kovalchuk;C. Haloun;A. J. Domb
  57. Macromolecules v.22 H. Y. Kwon;R. Langer
  58. Drugs Pharm. Sci. v.45 J. Kohn
  59. Biomaterials v.11 S. Pulapula;C. Li;J. Kohn
  60. Biomaterials v.21 B. S. Kim;J. S. Hrkach;R. Langer
  61. J. Biomed. Mater. Res. v.24 M. Yoshida;M. Asano;M. Kumakura;R. Katakai;T. Mashima;H. Yuasa;K. Imai;H. Yamanaka
  62. Ph. D. Thesis J. Helder
  63. J. Biomed. Mater. Res. Symposium v.5 J. M. Anderson;D. F. Gibbons;R. L. Martin;A. Hiltner;R. Woods
  64. J. Biomed. Mater. Res. v.24 J. Helder;J. Dijkstra;J. Feijen
  65. Polym. J. v.20 M. Asano;M. Yoshida;I. Kaetsu;R. Katakai;T. Mashimo;H. Yuasa;K. Imai;K. Yamanaka
  66. J. Biol. Chem. v.269 J. C. Myers;H. Yang;A. Dlppolito;A. Presente;M. K. Miller;A. S. Dion
  67. Current Opinion in Structural Biology v.3 M. van der Rest;P. Bruckner
  68. N. Engl. J. Med. v.326 D. J. Prockop
  69. Nucleic Acids Res. v.26 V. S. Trubetskoy;V. G. Vudker;L. J. Hanson;P. M. Slattum;J. A. Wolff;J. E. Hagstrom
  70. Pharm. Res. v.13 B. G. Muller;H. Leuenberger;T. Kissel
  71. Postgrad. Med. J. v.71 J. C. Doughty;J. H. Anderson;N. Willmott;C. S. McArdle
  72. Yao Hsueh Hsueh Pao v.28 Y. H. Cheng;G. T. Liao;S. X. Hou;L. Li;M. Zhang
  73. Cancer Chemother. Pharmacol. v.29 R. Verrijk;I. J. Smolders;J. G. McVie;A. C. Begg
  74. Drugs Exp. Clin. Res. v.11 S. S. Davis;I. M. Hunneyball;L. Illum;J. H. Rateliffe;A. Smith;C. G. Wilson
  75. Boll. Chim. Farm v.137 A. A. Bosela;M. M. el-Sayed;M. I. Mahmoud
  76. Boll. Chim. Farm. v.130 E. Iseri;M. T. Ercan;H. S. Kas;A. A. Hincal
  77. Biomaterials v.12 C. H. Yan;X. W. Li;X. L. Chen;D. Q. Wang;D. C. Zhong;T. Z. Tan;H. Kitano
  78. J. Biomater. Sci. Polym. Ed. v.6 J. K. Rao;D. V. Ramesh;K. P. Rao
  79. Invest. Opthalmol. Vis. Sci. v.40 T. Yasukawa;H. Kimura;Y. Tanaba;H. Miyamoto;Y. Honda;Y. Ikada;Y. Ogura
  80. Hua His Ko Ta Hsueh Hsueh Pao v.26 Z. Zhang;B. Lu;G. Shu;H. Xie;Q. Yi;Y. He;J. Wang
  81. Yao Hsueh Hsueh Pao v.30 J. H. Wang;B. Lu;P. L. Xu;D. Y. Bao;Z. R. Zhang
  82. Int. J. Pharm. v.193 D. K. Chowdhury;A. K. Mitra
  83. Thromb. Haemost. v.82 R. Herrmann;G. Schmidmaier;B. Markl;A. Resch;I. Hahnel;A. Stemberger;E. Alt
  84. Biomaterials v.9 J. M. Schakenraad;J. A. Oosterbaan;P. Nieuwenhuis;I. Molenaar;J. Olijslager;W. Potman;M. J. Eenink;J. Feijen
  85. Minckler. Amer. J. Ophthalmology v.109 B. Hasty;D. K. Heuer;D. S. Minckler
  86. Archives Ophthalmology v.107 D. G. Hwang;W. H. Stern;P. H. Hwang;L. A. MacGowan-Smith
  87. Am. J. Ophthalmology v.109 Y. E. Chem;B. Gebhardt;J. J. McReidy;H. E. Kaufman
  88. Biomaterials v.5 J. Kopecek
  89. Pharm. Res. v.9 H. Brondsted;J. Kopecek
  90. Science v.223 M. Saffran;G. S. Kumar;C. Savariar;J. C. Burnham;F. Williams;D. C. Neckers
  91. Polymer v.20 D. K. Gilding;A. M. Reed
  92. Cell Transpl. v.2 D. J. Mooney;G. Organ;J. P. Vacanti;R. Langer
  93. Biodegradable Polymers as Drug Delivery Systems D. H. Lewis;M. Chasin(Ed.);R. Langer(Ed.)
  94. Kor. Polym. J. v.5 G. I. Shin;J. H. Kim;S. H. Kim;Y. H. Kim
  95. Polymer (Kor.) v.22 J. S. Lee;D. J. Choo;S. H. Kim;Y. H. Kim
  96. J. Control. Rel. v.28 H. Okada;M. Yamamoto;T. Heya;Y. Inoue;K. Kamei;Y. Ogawa;H. Touchi
  97. Int. J. Pharm. v.72 T. Heya;H. Okada;Y. Ogawa;H. Touchi
  98. J. Control. Rel. v.28 J. Mestecky;Z. Moldoveanu;N. Novak;W. Q. Huang;R. M. Gilly;J. K. Stags;D. Schafer;R. W. Coupans
  99. Handbook of Biodegradable Polymers J. Heller;A. J. Domb(Ed.);J. Kost(Ed.);D. M. Wiseman(Ed.)
  100. U.S. Patent 4,079,038 N. S. Choi;J. Heller
  101. U.S. Patent 4,093,709 N. S. Choi;J. Heller
  102. U.S. Patent 4,131,648 N. S. Choi;J. Heller
  103. U.S. Patent 4,138,344 N. S. Choi;J. Heller
  104. U.S. Patent 4,180,646 N. S. Choi;J. Heller
  105. Polymeric Delivery Systems R. C. Capozza;S. L. Sendelbeck;W. J. Balkenhol;R. J. Kostelnik(Ed.)
  106. J. Control. Res. v.6 J. Heller;S. Y. Ng;D. W. Penhale;B. K. Fritzinger;L. M. Sanders;R. A. Burns;M. G. Gaynon;S. S. Bhosale
  107. J. Polym. Sci., Polym. Lett., Ed. v.18 J. Heller;D. W. Penhale;R. F. Helwing
  108. Macromolecular Synthesis v.11 S. Y. Ng;D. W. Penhale;J. Heller
  109. J. Control. Rel. v.31 L. W. Seymour;R. Duncan;J. Duffy;S. Y. Ng;J. Heller
  110. J. Control. Rel. v.14 Y. F. Maa;J. Heller
  111. Advances in Polymer Sci. v.107 J. Heller
  112. J. Control. Rel. v.1 J. Heller;B. K. Fritzinger;S. Y. Ng;D. W. Penhale
  113. J. Control. Rel. v.13 J. Heller;A. C. Chang;G. Rodd;G. M. Grodsky
  114. Biomaterials v.11 J. Heller;S. Y. Ng;B. K. Fritzinger;K. V. Roskos
  115. Biomaterials v.16 K. V. Roskos;B. K. Fritzinger;S. S. Rao;G. C. Armitage;J. Heller
  116. J. Control. Rel. v.21 P. Wuthrich;S. Y. Ng;K. Fritzinger;K. V. Roskos;J. Heller
  117. Macromolecules v.25 J. Heller;S. Y. Ng;B. K. Fritzinger
  118. Chem. Rev. v.72 H. R. Allcock
  119. Makromol. Chem. Macromol. Symp. v.6 H. R. Allcock
  120. Biomaterials v.13 H. R. Allcock
  121. Biodegradable Polymers as Drug Delivery Systems H. R. Allcock;R. Langer(Ed.);M. Chasin(Ed.)
  122. J. Biomed. Mater. Res. v.21 C. T. Laurencin;H. J. Koh;T. X. Neenan;H. R. Allcock;R. Langer
  123. Macromolecules v.29 H. R. Allcock;S. J. OConnor;D. L. Olmeijer;M. E. Napierala;C. G. Cameron
  124. Polymer Preprints v.41 H. R. Allcock;A. Ambrosio
  125. Biomaterials v.15 H. R. Allcock;S. R. Pucher;A. G. Scopelianos
  126. Macromolecules v.29 H. R. Allcock;G. K. Dudley
  127. Inorg. Chem. v.21 H. R. Allcock;T. J. Fuller;K. Matsumura
  128. J. Am. Chem. Soc. v.112 S. Cohen;M. C. Bano;K. B. Visscher;M. Chow;H. R. Allcock;R. Langer
  129. J. Biomed. Mater. Res. v.19 K. W. Leong;B. C. Brott;R. Langer
  130. J. Polym. Sci. Polym. Chem. v.25 A. J. Domb;R. Langer
  131. Macromolecules v.20 K. W. Leong;V. Simonte;R. Langer
  132. Macromolecules v.21 A. J. Domb;E. Ron;R. Langer
  133. Macromolecules v.22 A. J. Domb;C. E. Gallardo;R. Langer
  134. Biomaterials v.11 A. J. Domb
  135. J. Macromol. Sci. Chem. v.A22 A. Albertsson;S. Lundmark
  136. J. Orthop. Res. v.11 C. Laurencin;T. Gerhart;P. Witschger;R. Satcher;A. J. Domb;P. Hanff;L. Edsberg;W. Hayes;R. Langer
  137. Providing Pharmaceutical Access to the Brain, Methods in Neuroscience v.21 A. J. Domb;I. Ringel;T. R. Flanaga(Ed.);D. F. Emerich(Ed.);S. R. Winn(Ed.)
  138. Biomedical Applications of Synthetic Biodegradable Polymers C. T. Laurencin;S. E. Ibim;R. Langer;J. O. Hollinger(Ed.)
  139. Biomaterials v.16 A. J. Domb;R. Nudelman
  140. Makromol. Chem. Macromol. Symp. v.60 D. C. Pepper
  141. J. Polym. Sci. v.62 D. C. Pepper
  142. Dokl. Akad. Nauk. Uzb. USSR v.7 A. Alvotidinov
  143. J. Appl. Polym. Sci. v.10 F. Leonard;R. A. Kurkarni;G. Brandes;J. Nelson;J. J. Cameron
  144. Prog. Polym. Sci. v.9 J. Kopecek;K. Ulbrich
  145. J. Biomed. Mater. Res. v.14 W. R. Vezin;A. T. florence
  146. J. Biomed. Mater. Res. v.7 A. F. Hegyeli
  147. Invest. New Drugs v.10 J. Kattan;J. P. Droz;P. Couvreur;J. P. Marino;A. Boutan-Laroze;P. Rougier;P. Brault;H. Vranckx;J. X. Grognet;X. Morge;L. Sancho-Garnier
  148. Biomaterials v.11 R. H. Muller;C. Lherm;J. Herbort;P. Couvreur
  149. Cancer Chemother. Pharmacol. v.26 C. Verdun;F. Brasseur;H. Vranckx;P. Couvreur;M. Roland
  150. Appl. Biochem. Biotechnol. v.10 P. Maincent;J. P. Devissaguet;R. LeVerge;P. A. Sado;P. Couvreur
  151. J. Appl. Polym. Sci. v.39 K. J. Zhu;X. Lin;S. Yang
  152. J. Biomed. Mater. Res. v.30 B. Ronneberger;W. J. Kao;J. A. Anderson;T. Kissel
  153. Nature v.388 B. Jeong;Y. H. Bae;D. S. Lee;S. W. Kim
  154. J. Control. Rel. v.62 B. Jeong;Y. K. Choi;Y. H. Bae;G. Zentner;S. W. Kim
  155. Bioconjug. Chem. v.7 M. X. Tang;C. T. Redemann;F. C. Szoka
  156. J. Control. Rel. v.63 B. Jeong;Y. H. Bae;S. W. Kim
  157. World Biomat. Cong. Trans. v.Ⅲ B. Jeong;Y. H. Bae;S. W. Kim
  158. Macromol. Chem. Phys. v.196 P. Y. Yeh;P. Kopeckova;P. Kopecek
  159. Macromol. Chem. Phys. v.197 H. Ghandehari;P. Kopeckova;P. Y. Yeh;P. Kopecek
  160. Bioconjug. Chem. v.6 D. Putnam;P. Kopecek
  161. Pharm. Res. v.12 S. Kamei;P. Kopecek
  162. J. Control. Res. v.59 T. Minko;P. Kopeckova;P. Kopecek
  163. Polymer Preprints v.41 D. Wang;P. Kopeckova;T. Minko;V. Nanayakkara;P. Kopecek
  164. J. Control. Rel. v.62 K. Yasugi;Y. Nakasaki;M. Kao;K. Kataoka
  165. J. Pharm. Sci. v.87 S. Katayose;K. Kataoka
  166. Science v.283 A. Harada;K. Kataoka
  167. J. Biomed. Mater. Res. v.42 H. Suh;B. Jeong;R. Rathi;S. W. Kim
  168. J. Control. Rel. D. W. Grijpma;J. Feijen
  169. Pharm. Res. v.17 Y. Lim;S. Han;H. Kong;Y. Lee;J. Park;B. Jeong;S. W. Kim