Journal of Plant Biotechnology

The Korean Society of Plant Biotechnology (한국식물생명공학회)
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Molecular Characterization of Brassica Pollen Allergen

  • Toriyama, Kinya (Graduate School of Agricultural Science, Tohoku university, Japan) ;
  • Okada, Takashi (Graduate School of Agricultural Science, Tohoku university, Japan)
  • Published : 2000.05.01
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Abstract

Allergy to Brassica pollen has been reported in some countries. We have cloned a cDNA encoding a Brassica pollen allergen, Bra r 1. Bra r 1 belongs to a new family of $Ca^{2+}$-binding proteins, characterized by the presence of two EF-hand calcium-binding domains. Bra r 1 was detected in the tapetum, microspores, pollen coat and pollen tubes, indicating Bra r 1 is involved in pollen pistil interaction and pollen tube growth. We have engineered the hypoallergenic mutants of Bra r 1 for immunotherapy. Here we describe the review of molecular characterization of Bra r 1.

Keywords

References

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