대한의생명과학회지 (Biomedical Science Letters)
- 제6권1호
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- Pages.37-43
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- 2000
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- 1738-3226(pISSN)
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- 2288-7415(eISSN)
흰쥐에 있어서 피부노출 차단이 피부조직의 Xanthine Oxidase 활성에 미치는 영향
Effect of Occlusion on the Activities of Dermal Xanthine Oxidase in Rats
초록
흰쥐에 있어서 피부의 공기차단이 피부조직의 xanthine oxidase (XO) 활성에 미치는 영향을 검토하고자 직경 46 mm, 높이 10 mm인 petri dish-shaped glass chamber에 순간접착제 (
To investigate an impact of skin occlusion on the dermal xanthine oxidase (XO) activity, the dorsal part in rats was covered with closed petri dish-shaped chamber, 46 mm in diameter and 10 mm in height, which was made of glass. The crack between top of chamber and skin was sealed by an adhesive agent. After 5 days, the quantity of sweat accumulation was about 400 mg, whereas after 10 days that was decreased about to 21 mg. The 5 days skin occlusion showed the more increased activity of dermal XO compared with the control, and the increased ratio of enzyme activity to the control was higher than that of 10 days skin occlusion, with the increase being associated with sweat accumulation in chamber. Furthermore, the V