전자공학회논문지SC (Journal of the Institute of Electronics Engineers of Korea SC)

대한전자공학회 (The Institute of Electronics and Information Engineers)
권호 표지

능동형 박막 광도파로 칼슘 이온 센서의 개발

Development of Active thin Film Optical Waveguide $C^{2+}$ -ion Sensor

  • Lee, Su-Mi (Dept.of Sensor Engineering, Kyungpook National University) ;
  • Gang, Sin-Won (Dept.of Sensor Engineering, Kyungpook National University)
  • 발행 : 2000.07.01
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

고분자 이온 감응막을 광도파로로 이용한 새로운 형태의 센서소자를 제작하여 칼슘이온의 농도 변화에 따른 그 특성을 평가하였다. 광도파로 소자는 실리카 유리기판에 기존의 반도체 사진식각법 (photolitho-graphy)을 이용하여 도파로가 형성되어질 부분을 에칭한 후 감지막을 스핀코팅법으로 코팅하여, 그 자체를 도파로로 이용한 고속 응답의 새로운 형태의 센서소자를 제작하였다. 도파로로 사용된 감지막은 칼슘이온에 대해 특이성을 가지는 변색성 이온감응물질인 ETH5294, 중성이온감응물질인 K23El, anionic site인 NaTm(CF/sub 3/)/sub 2/PB, 가소제인 DOP 및 PVC-PVAC-PVA 폴리머를 THF 용매에 녹여 스핀 코팅법으로 제작하였다. 여러 가지 변수에 따른 센서의 특성을 평가하기 위하여 도파로의 두께(즉, 감지막의 두께), 변색성 이온감응물질의 농도, 각 모드 변화에 따른 센서의 감응특성을 비교 평가하였다. 제작된 센서는 칼슘이온에 대해 1×10­6∼1M의 측정 범위를 가지며, 1×10­⁴∼1×10­¹M 영역에서 선형성을 가지며, 기존의 광학적 측정 방법인 분광분석법에 비해 높은 감도를 나타냄을 확인하였다.

A new functional organic thin film optical waveguide ion sensor is designed, which can select a specific ion, i.e., $Ca^{2+}$ -ion. The sensing membrane was composed of PVC-PVAC-PVA copolymer matrix based on anionic cation-selective chromoionophor(ETH5294), neutral ionophore(K23El), anionic site and plasticizer and it was coated on the etched glass substrate as embeded type optical waveguide itself. The sensor sensitivity dependence on waveguide length and thickness, contence of chromoionophore, and each mode was investigated. And this sensor could detect $Ca^{2+}$ ion in concentrations ranging from 1$\times$10­6~1M(with 0.05M tris-HCI buffer solution of pH7.4) by measuring the absorbance change at 514nm of light. Utilizing thin film membrane, the fast response time and high sensitivity are obtained. Also, it is expected that this sensor can be applied to various biochemical important ions.ons.

키워드

참고문헌

  1. K. Seiler, W. E. Morf, B. Rusterholz and W. Simon, 'Design and Characterization of a Novel Ammonium Ion Selective Optical Sensor Based on Neutral Ionophores', Analy. Scien., vol. 5, pp. 557-561, 1989
  2. S. Ozawa, Peter C. Hauser, K. Seiler, Susie S. S. Tan, W. E. Morf, and W. Simon, 'Ammonia-Gas-Selective Optical Sensors Based on Neutral Ionophores', Anal. Chem., vol. 63, pp. 640-644, 1991 https://doi.org/10.1021/ac00006a017
  3. U. E. Spichiger, D. Freiner, E. Bakker, T. Rosatzin and W. Simon, 'Optodes in clinical chemistry : potential and limitations', Sensors and Actuators B, vol. 11, pp. 263-271, 1993 https://doi.org/10.1016/0925-4005(93)85264-B
  4. K. Watanabe, E. Nakagawa, H. Yamada, H. Hisamoto, and K. Suzuk, 'Lithium Ion Selective Optical Sensor Based on a Neutral Ionophore and Lipophilic Anionic Dye', Anal. Chem., vol. 65, pp. 2704-2710, 1993 https://doi.org/10.1021/ac00067a028
  5. W. E. Morf, K. Seiler, B. Rusterholz, and W. Simon, 'Design of a Calcium-Selective Optode Membrane Based on Neutral Ionophores', Anal. Chem., vol. 62, pp. 738-742, 1990 https://doi.org/10.1021/ac00206a018
  6. D. A. Stephens and P. W. Bohn, 'Long path length absorption measurements in thin dielectric films', Anal. Chem. vol. 59, pp. 2563-2566, 1987 https://doi.org/10.1021/ac00148a007
  7. R. Narayanaswamy and F. Sevilla III, 'Optical fiber sensors for chemical species', J. Phys. E 21, pp. 10-17, 1988 https://doi.org/10.1088/0022-3735/21/1/001
  8. W. F. Love and L. J. Button, 'Optical characteristics of fiber optic evanescent wave sensors', in Chemical Biochemical and M. T. Wlodarzyk, eds., Proc. Soc. Photo-Opt. Instrum. Eng. vol. 990, pp. 175-180, 1988
  9. S. W. Kang, K. Sasaki and H. Minamitani, 'Sensitivity analysis of a thin-film optical waveguide biochemical sensor using evanescent field absorption', Appl. Opt., 32, pp. 3544-3549, 1993
  10. S. S. Saavedra and W. M. Reichert, 'A flow cell for mode specific, integrated optical waveguide spectroscopy in aqueous superstrates', Appl. Spectrosc., vol. 44, pp. 1420-1423, 1990
  11. P. H. Paul, and G. Kychakoff, 'Fiber-optic evasecnt wave methane gas sensor using optical absorption for the 3.392-${\mu}m$ line of a He-Ne laser', Opt. Lett., 12, pp. 437-439, 1987
  12. S.W. Kang, 'Biochemical sensing by evanescent field absorption on thinfilm integrated optical waveguide', SICE '91, July 17-19, Yonejawa, pp. 931-934, 1991
  13. R. Ulrich and R. Rorge, 'Measurement of thin film parameters with a prism coupler', Appl. Opt., vol.12, pp 2901-2908, 1973
  14. S. T. Kirsch, 'Determining the refractive index and thickness of thin films from prism coupler measurements', Appl. Opt., vol. 20, pp. 2085-2089, 1981