Journal of Nutrition and Health

The Korean Nutrition Society (한국영양학회)
권호 표지

The Study of Relationship among Serum Leptin, Nutritional Status, Serum Glucose and Lipids of Middle-school Girls

일부 사춘기 여중생의 혈청 Leptin 함량과 영양소섭취상태 및 혈당, 혈청지질과의 상관관계 연구

  • 김미현 (숙명여자대학교 식품영양학과) ;
  • 승정자 (숙명여자대학교 식품영양학과)
  • Published : 2000.01.01
Download PDF
⟨ Previous Next ⟩

Abstract

The purpose of this study was to investigate the relationship among urn leptin, nutritional status, and urn lipids, glucose of 99 middle school girls residing in Kyluggi-do, Korea. Subjects were assigned to one of three groups such as underweight(BMI < 20, n=38), normal(20$\leq$BMI<25, n=36) and over weight(BMI$\geq$25, n=25) groups. The nutritional status of the subjects was evaluated by anthropometric measurements, questionnaires, 24-hr dietary recalls and blood anal),sis. The results were as follows : The mean age, body weight, height and BMI were 13.93 years, 55.19kg, 158.40cm and 21.96kg/㎡ respectively. The mean menarche age of the subjects was 12.64 years and the mean daily energy intake was 94.22% off RDA for Koreans. The energy ratio from carbohydrate fat and protein was 63: 24: 13. Underweight group showed the lowest intakes of oils and fats among three groups(p<0.05). The mean serum levels of leptin, glucose, total cholesterol, HDL-cholesterol. LDL-cholesterol and triglyceride were 10.57ng/ml 78.80mg/dl, 12.29mg/dl, 48.07mg/dl, 93.50mg/dl and 78.61mg/d1, respectively. The mean atherogenic index was 2.37. There were significant increases in serum leptin, glucose, LDL-cholesterol, triglyceride and atherogenic index of subjects with increases in their BMIs. Serum leptin showed a significantly positive correlation with BMI(p<0.001), body fat percent(p<0.001). When BMI was adjused, serum leptin showed a significantly positive partial correlations with intakes of animal protein(p<0.05), milks and animal foods(p<0.05), Serum leptin showed a significantly positive correlation with serum glucose(p<0.05) total cholesterol(p<0.01), LDL-cholesterol(p<0.001), triglyceride(p<0.001) and atherogenic index(p<0.001), however, it had significantly negative correlations with HDL-cholesterol(p<0.05). Therefore, these results suggest that the increase of serum levels of leptin may elevate the risk of cardiovascular disease and lipids and some nutrient intakes may be related with serum leptin levels. (Korean J Nutrition 33(1) : 49-58, 2000)

Keywords

References

  1. Nutrition in Adolescence Adolescent life-style and eating behavior, eating disorder Mahan LK;Rees JM
  2. Korean J Nutition v.26 no.2 The prevalence of obesity and it's related factors of high school girls in the large cities Kim HS;Lee LH
  3. The Korean Nutirion Society v.30 no.7 The Prevalence of childhood and adolescent obesity over the last 18 years in seoul area Kang YJ;Hong CH;Hong YJ
  4. The Journal of the Academy of Family Medicine v.16 no.11S Knowledge of body image and weight control behavior of junior high school girls in rural area Hong EK;Park YS;Shin YS;Park HS
  5. The Journal of the Academy of Family Medicine v.17 no.11S Factors that influence adolescents' satisfaction to body inage and their weight control behavior Song HJ;Ahn SH;Park MS;Yoo TU;Choi YI
  6. Nature v.372 Positional cloning of the mouse obese gene and its human homologue Zhang Y;Proenca R;Maffel M;Barone M;Leopold L;Friedman JM
  7. Proc Natl Acad Sci v.94 Physiological response to long-term peripheral and central leptin infusion in lean and obese mice Halaas JL;Boozer C;Blair-West J;Fidahusein N;Dentons DA;Friedman JM
  8. Science v.269 Effects of the obese gene product on body weight regulation in ob / ob mice Pellymounter MA;Cullen MJ;Baker MB;Hecht R;Winters D;Boone T
  9. N Engl J Med v.334 Serum immunoreactive-leptin concertrations in normal-weight and obese humans Considine RV;Sinha MK;Heiman ML;Kriauciunas A;Stephens TW;Nyce MR;Ohannesian JP;Marco CC;Mckee LJ;Bauer TL;Caro JF
  10. Clin Endocrinology v.46 Serum leptin concentrations in patients with anorexia nervosa, bulimia nervosa and non-specific eating disorders correlate with the body mass index but are indepedent of the respective disease Ferron F;Considine RV;Peino R;Lado IG;Dieguez C;Casanueva FF
  11. Korean J Community Nutrition v.3 no.2 An ecological study on eating behavior of middle school in Seoul Kim JH;Choi JH;Lee MJ;Moon SJ
  12. Clin Chem v.18 Estimation of concentration of low density cholesterol without use the preparation ultracentrifuge Friedwald WT;Levy RI;Fredrickson DS
  13. Recommended dietary allowances for Koreans(6th revision) The Korean Nutrition Society
  14. J Korean Pediatr Soc v.32 A study on blood pressure measurement of children in Seoul area Choi Y;Lee CY;Hong CE;Lee SI
  15. J Korean Pediatr Soc v.35 no.11 A study on obesity, blood pressure, blood cholesterol and Apo B, and, Urine Na and K of middle school student in Seoul area CHoe YH;Park KY;Ha IS;Chung HI;Choi Y;Kim JK
  16. The Korean Nutrition Society v.30 no.3 Nutritional status of junior high school students Ha MJ;Key SH;Lee HS;Seo SJ;Kang YJ;Kim CI
  17. J Korean Soc Food Nutr v.23 no.1 A study on the relationship between dietary intakes and the obesity of middle school students in Seoul Cho JE;Kim JH;Song KH
  18. Korean J Community Nutrition v.7 no.2 The dietary behavior and Nutrition status of the youth in rural area of Korea Lee GS;Yoo YS
  19. 95 National Nutrition Survey Report Ministry of health and welfare
  20. Prevention of Coronary Heart Disease: Report of a WHO Expert Committee WHO
  21. Food Composition table(fifth revision.) National Rural Living science Institute, RDA
  22. Sook-Myung Journal of Science for Better Living v.13 A study on the nutrient intakes from purchased foods in elementary, middle and high school students Lee MS;Cho HK;Sung CJ
  23. J Korean Pediatr Soc v.41 no.7 Serum leptin concentration in Korean children Choe YH;Kim SK;Hyun IY
  24. Journal of Korean Society for the study of Obesity v.6 no.2A The role of leptin Choi WH
  25. J Korean Pediatr Soc v.41 no.6 Serum leptin levels in children with obesity Lee BC;Song MY;Sur BK
  26. J Clin Endocrin Metab v.82 no.2 Sexual dimorphism in plasma leptin concentration Saad MF;Damani S;Gingerich RL;Riad-Gabriel MG;Khan A;Boy-adjian R;Jinagouda SD;El-Tawil K;Rude RK;Kamdar V
  27. Horm Res v.14 Relation of race, age, and sex, hormone differences to serum leptin concentrations in children and adolescents Ambrosius WT;Compton JC;Bowsher RR;Paratt JH
  28. Int J Obes v.21 Letin serum levels in normal weight and obese children and adolescents: relationship with age, sex,pubertal development, body mass index and insulin Falorni A,Bini V;Molinari D;Papi F;Ceri F;Stefano GD;Berioli MG;Bacosi ML;Contessa G
  29. Diabetic Medicine v.14 Plasma leptin in non-diabetic asian indians: aasociation with abdominal adiposity Ramachandran A;Snehalatha C;Vijay V;Satyavani K;Latha E;Haffner SM
  30. J Clin Endocrinol Metab v.82 no.9 Serum leptin levels in normal children: Relationship to age, gender,body mass index, pituitary-gonadal hormones, and pubertal stage Garacia mayor RV;Andrade MA;Rios M;Lage M;Dieguez C;Casanueva FC
  31. Pediatrics v.98 Serum leptin in children with osesity: Relation to gender and development Hassink SG;Sheslow DV;De Lancey E;Opentanova I;Considine RV;Caro JF
  32. J Korean Pediatr Soc v.37 no.11 A study on serum levels of cholesterol and HDL-cholesterol in normal elementary children Sim JK;Jeon MJ;Hwang MS
  33. Korean J Nutrition v.26 no.1 Eating behavior, Obesity and serum lipid levels in children Yim KS;Yoon EY;Kim CI;Kim KT;Kim CI;Mo SM;Choi HM
  34. Korean Journal of Lipidology v.3 no.2 A study on effects of dietary intake and obesity on serum lipid levels of elementary school children in a high-socioeconomic apartment complex in seoul Kim JH;Lee YN;Mo SM;Choi HM
  35. Korean J Community Nutrition v.2 no.2 Obesity, serum lipid and related Eating behaviors of school children Son SM;Lee JH
  36. Korean J Food & Nutr v.9 no.4 A study on blood pressure and blood constituents of middle-aged men obesity Lee HO;Park HS;Sung CJ
  37. Nutritional status, immune response and trace minerals in Korean urban young womem according to body mass index Lee HO
  38. Prod R Soc Lond v.140 The role of depot fat in the hypothalamic control of food intake in the rat Kennedy GR
  39. J Korean Pediatr Soc v.41 no.7 Serum leptin levels in obese children Ha Ka;Kim IR;Park MJ;Kong JH;Chung CY
  40. Am J Clin Nutr v.66 Leptin concentration in women is influenced by reginal distribution of adipose tissue Bennett FI;McFarlane Anderson N;Wilks R;Luke A;Cooper RS;Forrester TE
  41. Am J Clin Nutr v.67 Leptin and body composition of nigerians, jamaicansand US blacks Luke AH;Rotimi CN;Cooper RS;Long AE;Forrester TE;Wilks R;Bennett FI
  42. J Clin Endocrinol Metab v.82 no.10 Leptin is inversely related to age at menatche in human females Matkovic V;Ilich JZ;Skugor M;Badenhop NE;Goel P;Clairmont A;Klisovic D;Nahhas RW;Landoll JD
  43. Diabetes v.46 no.6 Circulationg leptin in normal children and during the dynamic phase of juvenile obesity: realtion to body fatness, energy metabolism, caloric intake, and sexual dimorphism Lahlou N;Landais P;De Boissieu D;Bougeres PF
  44. Nat Med v.1 Leptin levels reflect body lipid content in mice: Evidence for diet-induced resistance to leptin action Frederich RC;Hamann A;Anderson S
  45. Metabolism v.46 no.4 Effect of diet composition on leptin in lean subject Schrauwen P;Marken LW;Westerterp KR;Saris WH