Cytotoxic Cyclodepsipeptides of Bombycis corpus 101A

백강잠 101A의 세포독성 사이클로뎁시펩타이드 성분

  • Published : 2000.04.01

Abstract

From the MeOH extract of Bombycis corpus inoculated by Beauberia bassiana 101A, two cyclodepsipeptides, bassianolide (1) and beaubericin (2), were isolated and their structures were determined by one and two dimensional NMR studies. Compounds 1 and 2 exhibited cytotoxicity against cultured human tumor cell lines.

Keywords

References

  1. 중약대사전,완역판 김창민;신민교;안덕균;이경순
  2. Cytotoxic constituents of Bombycis corpus. v.43 Kwon,H.C.,Moon,H.I.,Choi,S.H.,Lee,J.O.,Cho,S.Y.,Jung,I.Y.Kim,S.Y;Lee,K.R
  3. J.Natl.Cancer Inst v.82 New colorimetric cytotoxicity assay for anticancer-drug screening Skehan,P.,Storeng.R.,Scudiero,D.,Monks,A.,McMahon,J.,Vistica,D.,Warren,J.T.Bodesch,H.,Kenney.S.;Boyd,M.R.
  4. J.Am.Chem.Soc v.118 Onchidin B : A New Cyclodepsipeptide from the Mollusc Onchidium sp Fernandez,R.,Rodriguez,J.,Quinoa,E.,Riguera,R.,Munoz,L.,Fernandez-Suarez,M.;Debitus,C
  5. The Journal of Antibiotics v.50 Roseocardin,A Novel cardiotonic cyclodepsipeptide from Trichothecium roseum TT103 Tsunoo,A.,Kamuo,M.,Taketomo,N.,Sato,Y.;Ajisaka,K
  6. v.42 Bassianolide a new insecticidal cyclodepsipeptide from Beauveria bassiana and Verticillium lecanii Kanaoka,M.Isogai,A.,Murakoshi,S.,Ichinoe,M.,Suzuki,A.;Tamura,S
  7. Beauveria bassiana.J.Nat.Prod v.58 Isolation of novel beauvericin analogues from the fungus Gupta,S.,Montllor,C.;Hwang,Y.S.